Literature DB >> 623102

A genetic study of immunoglobulin E.

J W Gerrard, D C Rao, N E Morton.   

Abstract

Path analysis gives evidence of genetic heritability (.425) for serum IgE levels. Complex segregation analysis indicates, in addition to significant polygenic heritability, a major regulatory locus RE, with homozygotes re/re maintaining persistently high levels of IgE. The gene frequency of re is .489, and the displacement is 1.67 standard deviations.

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Year:  1978        PMID： 623102      PMCID： PMC1685450     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  9 in total

1.  The Behavior of Bronchial Asthma as an Inherited Character.

Authors:  J Adkinson
Journal:  Genetics       Date:  1920-07       Impact factor: 4.562

2.  Skewness in commingled distributions.

Authors:  C J Maclean; N E Morton; R C Elston; S Yee
Journal:  Biometrics       Date:  1976-09       Impact factor: 2.571

3.  Physicochemical properties of reaginic antibody. V. Correlation of reaginic activity wth gamma-E-globulin antibody.

Authors:  K Ishizaka; T Ishizaka; M M Hornbrook
Journal:  J Immunol       Date:  1966-12       Impact factor: 5.422

4.  Raised levels of a new immunoglobulin class (IgND) in asthma.

Authors:  S G Johansson
Journal:  Lancet       Date:  1967-11-04       Impact factor: 79.321

5.  Serum IgE levels in parents and children.

Authors:  J W Gerrard; S Horne; P Vickers; J W MacKenzie; N Goluboff; J Z Garson; C S Maningas
Journal:  J Pediatr       Date:  1974-11       Impact factor: 4.406

6.  Genetic control of basal serum immunoglobulin E level and its effect on specific reaginic sensitivity.

Authors:  D G Marsh; W B Bias; K Ishizaka
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

7.  IgE levels in normal infants and mothers and an inheritance hypothesis.

Authors:  M Bazaral; H A Orgel; R N Hamburger
Journal:  J Immunol       Date:  1971-09       Impact factor: 5.422

8.  Analysis of family resemblance. 3. Complex segregation of quantitative traits.

Authors:  N E Morton; C J MacLean
Journal:  Am J Hum Genet       Date:  1974-07       Impact factor: 11.025

9.  Causes of variation in serum IgE levels in normal populations.

Authors:  F J Grundbacher
Journal:  J Allergy Clin Immunol       Date:  1975-08       Impact factor: 10.793
  9 in total
  30 in total

1.  Complex segregation analysis of the locus for beta-aminoisobutyric acid excretion (BAIB).

Authors:  S P Simpson; N E Morton
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

2.  Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma.

Authors:  A H Mansur; D T Bishop; S T Holgate; A F Markham; J F J Morrison
Journal:  Thorax       Date:  2004-10       Impact factor: 9.139

3.  Examining the association between childhood asthma and parent and grandparent asthma status: implications for practice.

Authors:  Melissa A Valerio; Patricia M Andreski; Robert F Schoeni; Katherine A McGonagle
Journal:  Clin Pediatr (Phila)       Date:  2010-06       Impact factor: 1.168

4.  Confirmation of genetic linkage between atopic IgE responses and chromosome 11q13.

Authors:  R P Young; P A Sharp; J R Lynch; J A Faux; G M Lathrop; W O Cookson; J M Hopkin
Journal:  J Med Genet       Date:  1992-04       Impact factor: 6.318

5.  Chronic sinopulmonary inflammatory diseases in adults with undetectable serum IgE in inner-city Chicago: a preliminary observation.

Authors:  Funlola Famuyiwa; Israel Rubinstein
Journal:  Lung       Date:  2012-02-07       Impact factor: 2.584

6.  Commingling and segregation analysis of blood pressure in a French-Canadian population.

Authors:  T Rice; C Bouchard; I B Borecki; D C Rao
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025

7.  Candidate gene loci in asthmatic and allergic inflammation.

Authors:  J Wilkinson; S T Holgate
Journal:  Thorax       Date:  1996-01       Impact factor: 9.139

Review 8.  Genetic control of IgE immune response.

Authors:  S Matsushita; T Sasazuki
Journal:  Clin Rev Allergy       Date:  1989

9.  Polymorphism in intron 1 of the interferon-gamma gene influences both serum immunoglobulin E levels and the risk for chronic hepatitis B virus infection in Polynesians.

Authors:  William Abbott; Edward Gane; Ingrid Winship; Stephen Munn; Colin Tukuitonga
Journal:  Immunogenetics       Date:  2007-01-09       Impact factor: 2.846

10.  Maximum likelihood estimation by counting methods under polygenic and mixed models in human pedigrees.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1979-03       Impact factor: 11.025
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