Literature DB >> 6223177

Normal exocytosis and endocytosis of lysosomal beta-hexosaminidase in a case of alpha 1-antitrypsin deficiency.

K Ullrich.   

Abstract

Secretion of lysosomal beta-hexosaminidase by cultivated skin fibroblasts and receptor-mediated endocytosis of leucocyte beta-hexosaminidase from a patient by cultivated non-parenchymal rat liver cells and skin fibroblasts were similar to that of a control proband. The results suggest normal oligosaccharide side chains of high mannose type on lysosomal enzymes in alpha 1-antitrypsin (AAT) deficiency.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6223177     DOI： 10.1007/bf01497781

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  18 in total

1.  The synthesis of complex-type oligosaccharides. III. Identification of an alpha-D-mannosidase activity involved in a late stage of processing of complex-type oligosaccharides.

Authors:  I Tabas; S Kornfeld
Journal:  J Biol Chem       Date:  1978-11-10       Impact factor: 5.157

2.  Systematic purification of five glycosidases from Streptococcus (Diplococcus) pneumoniae.

Authors:  L R Glasgow; J C Paulson; R L Hill
Journal:  J Biol Chem       Date:  1977-12-10       Impact factor: 5.157

Review 3.  alpha1-antitrypsin deficiency (first of two parts).

Authors:  J O Morse
Journal:  N Engl J Med       Date:  1978-11-09       Impact factor: 91.245

Review 4.  Comparative aspects of glycoprotein structure.

Authors:  R Kornfeld; S Kornfeld
Journal:  Annu Rev Biochem       Date:  1976       Impact factor: 23.643

5.  Enzymatic phosphorylation of lysosomal enzymes in the presence of UDP-N-acetylglucosamine. Absence of the activity in I-cell fibroblasts.

Authors:  A Hasilik; A Waheed; K von Figura
Journal:  Biochem Biophys Res Commun       Date:  1981-02-12       Impact factor: 3.575

6.  Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

Authors:  A Hasilik; E F Neufeld
Journal:  J Biol Chem       Date:  1980-05-25       Impact factor: 5.157

7.  Endocytosis of lysosomal enzymes by non-parenchymal rat liver cells. Comparative study of lysosomal-enzyme uptake by hepatocytes and non-parenchymal liver cells.

Authors:  K Ullrich; V Gieselmann; G Mersmann; K Von Figura
Journal:  Biochem J       Date:  1979-08-15       Impact factor: 3.857

8.  Evidence for lysosomal enzyme recognition by human fibroblasts via a phosphorylated carbohydrate moiety.

Authors:  K Ullrich; G Mersmann; E Weber; K Von Figura
Journal:  Biochem J       Date:  1978-03-15       Impact factor: 3.857

9.  Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups.

Authors:  A Hasilik; U Klein; A Waheed; G Strecker; K von Figura
Journal:  Proc Natl Acad Sci U S A       Date:  1980-12       Impact factor: 11.205

10.  Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.

Authors:  A Kaplan; D T Achord; W S Sly
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.