Literature DB >> 621787

Mutator and antimutator phenotypes of suppressed amber mutants in genes 32, 41, 44, 45, and 62 in bacteriophage T4.

S M Watanabe, M F Goodman.   

Abstract

Bacteriophage T4 genes 32, 41, 44, 45, 56, and 62 are essential to DNA replication. Amber mutants (suppressed by su+1, su+2, or su+3 bacteria) in these genes were examined for any mutator or antimutator effects on the reversion of a transition mutation. In every case except for mutations in gene 56, elevated or lowered error frequencies were observed. These results indicate the importance of all of the replicative proteins in the determination of error frequency.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 621787      PMCID： PMC353902     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA.

Authors:  S P CHAMPE; S BENZER
Journal:  Proc Natl Acad Sci U S A       Date:  1962-04-15       Impact factor: 11.205

2.  Mutator mutations in bacteriophage T4 gene 42 (dHMC hydroxymethylase).

Authors:  W E Williams; J W Drake
Journal:  Genetics       Date:  1977-07       Impact factor: 4.562

3.  Studies of the self-association of bacteriophage T4 gene 32 protein by equilibrium sedimentation.

Authors:  R B Carroll; K Neet; D A Goldthwait
Journal:  J Mol Biol       Date:  1975-01-25       Impact factor: 5.469

4.  Intracellular DNA-protein complexes from bacteriophage T4-infected cells isolated by a rapid two-step procedure. Characterization and identification of the protein components.

Authors:  C Manoil; N Sinha; B Alberts
Journal:  J Biol Chem       Date:  1977-04-25       Impact factor: 5.157

5.  Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4.

Authors:  N Muzyczka; R L Poland; M J Bessman
Journal:  J Biol Chem       Date:  1972-11-25       Impact factor: 5.157

6.  Ligase-defective bacteriophage T4. I. Effects on mutation rates.

Authors:  R E Koch; J W Drake
Journal:  J Virol       Date:  1973-01       Impact factor: 5.103

7.  Mutagenic effect of temperature-sensitive mutants of gene 42 (dCMP hydroxymethylase) of bacteriophage T4.

Authors:  C S Chiu; G R Greenberg
Journal:  J Virol       Date:  1973-07       Impact factor: 5.103

8.  The genetic control of spontaneous and induced mutation rates in bacteriophage T4.

Authors:  J W Drake
Journal:  Genetics       Date:  1973-04       Impact factor: 4.562

9.  A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases.

Authors:  N Sigal; H Delius; T Kornberg; M L Gefter; B Alberts
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

10.  Properties of the Escherichia coli in DNA binding (unwinding) protein: interaction with DNA polymerase and DNA.

Authors:  I J Molineux; M L Gefter
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205
View more
  2 in total

1.  A major role for bacteriophage T4 DNA polymerase in frameshift mutagenesis.

Authors:  L S Ripley; N B Shoemaker
Journal:  Genetics       Date:  1983-03       Impact factor: 4.562

2.  Single-strand binding protein enhances fidelity of DNA synthesis in vitro.

Authors:  T A Kunkel; R R Meyer; L A Loeb
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.