Literature DB >> 6206699

Collagenase and elastase in the serum of adjuvant arthritic rats.

N Al-Haik, D P Parrott, D A Lewis.   

Abstract

Collagenase and elastase activities in the serum of adjuvant arthritic rats declined with time as the disease progressed and did not parallel increases in alpha 1-macroglobulin or alpha 2-acute phase globulin levels. The fall in collagenase and elastase activities was accompanied by a decline in serum alpha 1-proteinase inhibitor levels. It was concluded that the fall in collagenase and elastase activities in serum was due to inactivation by serum anti-proteases.

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Year:  1984        PMID: 6206699     DOI: 10.1007/bf01978909

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  19 in total

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Authors:  D A Lewis; D P Parrott
Journal:  Br J Pharmacol       Date:  1976-11       Impact factor: 8.739

Review 2.  Human granulocyte elastase. Further delineation of its role in connective tissue damage.

Authors:  A Janoff
Journal:  Am J Pathol       Date:  1972-09       Impact factor: 4.307

Review 3.  Lipoprotein-polyanion-metal interactions.

Authors:  M Burstein; H R Scholnick
Journal:  Adv Lipid Res       Date:  1973

4.  Rat alpha2-acute phase globulin, a human alpha2-macroglobulin homologue. Interaction with plasmin and trypsin.

Authors:  K Ganrot
Journal:  Biochim Biophys Acta       Date:  1973-09-21

5.  The alpha 1-antitrypsin and alpha 2-macroglobulin content and the protease-inhibiting capacity of normal and pathological sera.

Authors:  F Miesch; J Bieth; P Metais
Journal:  Clin Chim Acta       Date:  1971-01       Impact factor: 3.786

6.  Elimination of 125-I-trypsin alpha-macroglobulin complexes from blood by reticuloendothelial cells in dogs.

Authors:  K Ohlsson
Journal:  Acta Physiol Scand       Date:  1971-02

7.  Measurement of alpha 1-antitrypsin in serum, by immunodiffusion and by enzymatic assay.

Authors: 
Journal:  Clin Chem       Date:  1974-03       Impact factor: 8.327

8.  Adjuvant-induced inflammatory disease in the rat: plasma levels of peptide hydrolases and protease inhibitors reflect disease activity.

Authors:  H P Schnebli
Journal:  Agents Actions       Date:  1979-12

9.  Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies.

Authors:  C B Laurell
Journal:  Anal Biochem       Date:  1966-04       Impact factor: 3.365

10.  CHEMOTHERAPY OF ARTHRITIS INDUCED IN RATS BY MYCOBACTERIAL ADJUVANT.

Authors:  B B NEWBOULD
Journal:  Br J Pharmacol Chemother       Date:  1963-08
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