Literature DB >> 6201200

5-A Fourier map of gramicidin A phased by deuterium-hydrogen solvent difference neutron diffraction.

R E Koeppe, B P Schoenborn.   

Abstract

Crystals of ion-free gramicidin A (P212121: a = 24.61, b = 32.28, c = 32.52) have been investigated using neutron diffraction. A difference analysis of crystals soaked in ethanol/H2O as opposed to ethanol-d6/D2O has led to single isomorphous replacement Fourier projections of the structure at 5-A resolution. The gramicidin dimer appears to be a 32-A-long cylinder oriented parallel to the c-axis in these crystals.

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Year:  1984        PMID： 6201200      PMCID： PMC1434879          DOI： 10.1016/S0006-3495(84)84186-7

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  12 in total

1.  The gramicidin A transmembrane channel: a proposed pi(L,D) helix.

Authors:  D W Urry
Journal:  Proc Natl Acad Sci U S A       Date:  1971-03       Impact factor: 11.205

2.  Conformation of the gramicidin A transmembrane channel: A 13C nuclear magnetic resonance study of 13C-enriched gramicidin in phosphatidylcholine vesicles.

Authors:  S Weinstein; B A Wallace; J S Morrow; W R Veatch
Journal:  J Mol Biol       Date:  1980-10-15       Impact factor: 5.469

3.  The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport.

Authors:  A Finkelstein; O S Andersen
Journal:  J Membr Biol       Date:  1981-04-30       Impact factor: 1.843

4.  Gramicidin A crystals contain two cation binding sites per channel.

Authors:  R E Koeppe; J M Berg; K O Hodgson; L Stryer
Journal:  Nature       Date:  1979-06-21       Impact factor: 49.962

Review 5.  Neutron scattering for the analysis of membranes.

Authors:  B P Schoenborn
Journal:  Biochim Biophys Acta       Date:  1976-04-13

6.  Biological function of gramicidin: selective inhibition of RNA polymerase.

Authors:  N Sarkar; D Langley; H Paulus
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

7.  Helical channels in crystals of gramicidin A and of a cesium--gramicidin A complex: an x-ray diffraction study.

Authors:  R E Koeppe; K O Hodgson; L Stryer
Journal:  J Mol Biol       Date:  1978-05-05       Impact factor: 5.469

8.  The tetramer d(CpGpCpG) crystallizes as a left-handed double helix.

Authors:  J L Crawford; F J Kolpak; A H Wang; G J Quigley; J H van Boom; G van der Marel; A Rich
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

9.  Conformation and molecular mechanisms of carriers and channels.

Authors:  D W Urry; M M Long; M Jacobs; R D Harris
Journal:  Ann N Y Acad Sci       Date:  1975-12-30       Impact factor: 5.691

10.  Structure of the gramicidin A channel: discrimination between the piL,D and the beta helix by electrical measurements with lipid bilayer membranes.

Authors:  E Bamberg; H J Apell; H Alpes
Journal:  Proc Natl Acad Sci U S A       Date:  1977-06       Impact factor: 11.205
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  5 in total

1.  Structure of gramicidin A.

Authors:  B A Wallace
Journal:  Biophys J       Date:  1986-01       Impact factor: 4.033

2.  Vibrational analysis of the structure of gramicidin A. I. Normal mode analysis.

Authors:  V M Naik; S Krimm
Journal:  Biophys J       Date:  1986-06       Impact factor: 4.033

Review 3.  Gramicidin A--phospholipid model systems.

Authors:  B Cornell
Journal:  J Bioenerg Biomembr       Date:  1987-12       Impact factor: 2.945

4.  The normal modes of the gramicidin-A dimer channel.

Authors:  B Roux; M Karplus
Journal:  Biophys J       Date:  1988-03       Impact factor: 4.033

5.  Conformation and orientation of gramicidin a in oriented phospholipid bilayers measured by solid state carbon-13 NMR.

Authors:  B A Cornell; F Separovic; A J Baldassi; R Smith
Journal:  Biophys J       Date:  1988-01       Impact factor: 4.033
  5 in total

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