Literature DB >> 6199515

Neoplastic transformation by E26 leukemia virus is mediated by a single protein containing domains of gag and myb genes.

K H Klempnauer, J M Bishop.   

Abstract

The genome of avian leukemia virus E26 shares homology with v-myb, the oncogene of avian myeloblastosis virus, and encodes a protein with an Mr of 135,000. Analyses of tryptic oligopeptides show that this protein is related to the proteins encoded by gag (Pr76gag) as well as v-myb (p45v-myb[AMV] ) and c-myb (p75c-myb). We found no evidence for the existence of additional myb-related proteins or subgenomic species of myb-related RNA in myeloblasts transformed by strain E26.

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Year:  1984        PMID： 6199515      PMCID： PMC255612     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

1.  Transcripts from the cellular homologs of retroviral oncogenes: distribution among chicken tissues.

Authors:  T J Gonda; D K Sheiness; J M Bishop
Journal:  Mol Cell Biol       Date:  1982-06       Impact factor: 4.272

2.  Transforming capacities and defectiveness of avian leukemia viruses OK10 and E 26.

Authors:  T Graf; N Oker-Blom; T G Todorov; H Beug
Journal:  Virology       Date:  1979-12       Impact factor: 3.616

3.  Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation.

Authors:  M Roussel; S Saule; C Lagrou; C Rommens; H Beug; T Graf; D Stehelin
Journal:  Nature       Date:  1979-10-11       Impact factor: 49.962

Review 4.  Leukemic transformation with avian myeloblastosis virus: present status.

Authors:  C Moscovici
Journal:  Curr Top Microbiol Immunol       Date:  1975       Impact factor: 4.291

5.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

6.  Myeloid and erythroid neoplastic responses to avian defective leukemia viruses in chickens and in quail.

Authors:  C Moscovici; J Samarut; L Gazzolo; M G Moscovici
Journal:  Virology       Date:  1981-09       Impact factor: 3.616

7.  A putative second cell-derived oncogene of the avian leukaemia retrovirus E26.

Authors:  D Leprince; A Gegonne; J Coll; C de Taisne; A Schneeberger; C Lagrou; D Stehelin
Journal:  Nature       Date:  1983 Nov 24-30       Impact factor: 49.962

8.  A joint produce of the genes gag and pol of avian sarcoma virus: a possible precursor of reverse transcriptase.

Authors:  H Oppermann; J M Bishop; H E Varmus; L Levintow
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

9.  Size and genetic content of virus-specific RNA in myeloblasts transformed by avian myeloblastosis virus (AMV).

Authors:  J H Chen; W S Hayward; C Moscovici
Journal:  Virology       Date:  1981-04-15       Impact factor: 3.616

10.  The genome and the intracellular RNAs of avian myeloblastosis virus.

Authors:  T J Gonda; D K Sheiness; L Fanshier; J M Bishop; C Moscovici; M G Moscovici
Journal:  Cell       Date:  1981-01       Impact factor: 41.582
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  5 in total

1.  A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C.

Authors:  S Fujiwara; R J Fisher; N K Bhat; S M Diaz de la Espina; T S Papas
Journal:  Mol Cell Biol       Date:  1988-11       Impact factor: 4.272

2.  An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.

Authors:  Johannes Zuber; Amy R Rappaport; Weijun Luo; Eric Wang; Chong Chen; Angelina V Vaseva; Junwei Shi; Susann Weissmueller; Christof Fellmann; Christof Fellman; Meredith J Taylor; Martina Weissenboeck; Thomas G Graeber; Scott C Kogan; Christopher R Vakoc; Scott W Lowe
Journal:  Genes Dev       Date:  2011-08-01       Impact factor: 11.361

3.  Activation of the c-myb locus is insufficient for the rapid induction of disseminated avian B-cell lymphoma.

Authors:  E S Pizer; T W Baba; E H Humphries
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

4.  Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia.

Authors:  Sumiko Takao; Lauren Forbes; Masahiro Uni; Shuyuan Cheng; Jose Mario Bello Pineda; Yusuke Tarumoto; Paolo Cifani; Gerard Minuesa; Celine Chen; Michael G Kharas; Robert K Bradley; Christopher R Vakoc; Richard P Koche; Alex Kentsis
Journal:  Elife       Date:  2021-02-02       Impact factor: 8.713

5.  Identification and characterization of the protein encoded by the human c-myb proto-oncogene.

Authors:  K H Klempnauer; C Bonifer; A E Sippel
Journal:  EMBO J       Date:  1986-08       Impact factor: 11.598
  5 in total

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