Literature DB >> 6198629

Molecular weight determination program.

C V Maina, G P Nolan, A A Szalay.   

Abstract

A computer program is described that will determine the molecular weight of DNA, RNA or protein molecules separated according to size by gel electrophoresis. It uses the sizes and migration distances of known molecules in a reference lane to compute a second or third order equation whose curve best fits the data points. It then computes the sizes of all molecules from this equation. Migration distances are measured and entered using an analog tablet. The program is written in Apple Pascal and designed to run on an Apple II Plus computer.

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Year:  1984        PMID： 6198629      PMCID： PMC321085          DOI： 10.1093/nar/12.1part2.695

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  4 in total

1.  Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.

Authors:  T Maniatis; A Jeffrey; H van deSande
Journal:  Biochemistry       Date:  1975-08-26       Impact factor: 3.162

2.  Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.

Authors:  P A Sharp; B Sugden; J Sambrook
Journal:  Biochemistry       Date:  1973-07-31       Impact factor: 3.162

3.  A computer program for determining the size of DNA restriction fragments.

Authors:  R G Duggleby; H Kinns; J I Rood
Journal:  Anal Biochem       Date:  1981-01-01       Impact factor: 3.365

4.  Cleavage of adenovirus type 2 DNA into six unique fragments by endonuclease R-RI.

Authors:  U Pettersson; C Mulder; H Deluis; P A Sharp
Journal:  Proc Natl Acad Sci U S A       Date:  1973-01       Impact factor: 11.205
  4 in total
  1 in total

1.  SPLINT: a cubic spline interpolation program for the analysis of fragment sizes in one-dimensional electrophoresis gels.

Authors:  C E Gariepy; M I Lomax; L I Grossman
Journal:  Nucleic Acids Res       Date:  1986-01-10       Impact factor: 16.971
  1 in total

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