Literature DB >> 6193629

Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells.

I Damjanov, P S Amenta, F T Bosman.   

Abstract

The light microscopic, electron microscopic and histochemical features of a highly malignant colonic tumor resected from a 39 year old man are presented. The tumor was composed predominantly of undifferentiated cells with focally admixed neuroendocrine, exocrine and squamous cells, occasionally arranged in an organoid manner. Histochemically the tumor contained argyrophilic cells as well as cells that reacted positively with the antibodies to alpha-1-antitrypsin, alpha-1-antichymotrypsin, carcinoembryonic antigen and lysozyme. The term "stem cell carcinoma of the intestine" is proposed for this highly malignant tumor composed of undifferentiated cells exhibiting only focally their multidirectional developmental capacity.

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Year:  1983        PMID： 6193629     DOI： 10.1007/bf00644789

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN： 0174-7398


  19 in total

1.  Keratin cytoskeletons in epithelial cells of internal organs.

Authors:  T T Sun; C Shih; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

2.  Carcinoma of the colon with undifferentiated, carcinoid, and squamous cell features.

Authors:  M Petrelli; E Tetangco; J D Reid
Journal:  Am J Clin Pathol       Date:  1981-04       Impact factor: 2.493

3.  APUD cells in teratomas.

Authors:  F T Bosman; J W Louwerens
Journal:  Am J Pathol       Date:  1981-08       Impact factor: 4.307

4.  Synthesis of alpha 1-antichymotrypsin and alpha 1-acid glycoprotein by human breast epithelial cells.

Authors:  S J Gendler; G B Dermer; L M Silverman; Z A Tökés
Journal:  Cancer Res       Date:  1982-11       Impact factor: 12.701

5.  The amphicrine (endo-exocrine) cells in the human gut, with a short reference to amphicrine neoplasias.

Authors:  M Ratzenhofer; L Auböck
Journal:  Acta Morphol Acad Sci Hung       Date:  1980

6.  Adenocarcinoma of the colon with choriocarcinoma in its metastases.

Authors:  C H Park; J D Reid
Journal:  Cancer       Date:  1980-08-01       Impact factor: 6.860

7.  The endodermal origin of the endocrine cells of an adenocarcinoma of the colon of the rat.

Authors:  W F Cox; G B Pierce
Journal:  Cancer       Date:  1982-10-15       Impact factor: 6.860

8.  Alpha-1-antitrypsin immunoreactivity in gastric carcinoid.

Authors:  M B Ray; K Geboes; F Callea; V J Desmet
Journal:  Histopathology       Date:  1982-05       Impact factor: 5.087

9.  Identification of carcinoembryonic antigen in the C-cell of the normal thyroid.

Authors:  T Kodama; M Fujino; Y Endo; T Obara; Y Fujimoto; T Oda; T Wada
Journal:  Cancer       Date:  1980-01-01       Impact factor: 6.860

10.  Morphological identification of alpha-I-antitrypsin in the human small intestine.

Authors:  K Geboes; M B Ray; P Rutgeerts; F Callea; V J Desmet; G Vantrappen
Journal:  Histopathology       Date:  1982-01       Impact factor: 5.087
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  8 in total

1.  Small cell carcinoma of rectum: a case report.

Authors:  Enver Ihtiyar; Cem Algin; Serap Isiksoy; Ersin Ates
Journal:  World J Gastroenterol       Date:  2005-05-28       Impact factor: 5.742

2.  Composite tumor of the esophagus with tripartite differentiation.

Authors:  T Nishimaki; S Nakagawa; K Aizawa; T Suzuki; K Hatakeyama; H Watanabe
Journal:  Dig Dis Sci       Date:  1997-05       Impact factor: 3.199

Review 3.  Ectopic adrenocorticotropin syndrome associated with undifferentiated carcinoma of the colon showing multidirectional neuroendocrine, exocrine, and squamous differentiation.

Authors:  R Onishi; T Sano; Y Nakamura; S Namiuchi; S Sawada; C Ihara; A Shimatsu
Journal:  Virchows Arch       Date:  1996-02       Impact factor: 4.064

4.  Expression of a marker for colonic crypt base cells is correlated with poor prognosis in human colorectal cancer.

Authors:  A A van der Wurff; J ten Kate; P T Marx; E P van der Linden; C C Beek; F J Bovelander; J Dekker; W N Dinjens; M F von Meyenfeldt; J W Arends; F T Bosman
Journal:  Gut       Date:  1998-01       Impact factor: 23.059

Review 5.  Composite glandular-carcinoid tumour of the terminal ileum.

Authors:  N M Varghese; A M Zaitoun; S M Thomas; A Senapati; A Theodossi
Journal:  J Clin Pathol       Date:  1994-05       Impact factor: 3.411

Review 6.  Carcinomas of the colon with multidirectional differentiation. Report of two cases and review of the literature.

Authors:  P Novello; P Duvillard; S Grandjouan; D Elias; P Rougier; C Bognel; M Prade
Journal:  Dig Dis Sci       Date:  1995-01       Impact factor: 3.199

7.  Mixed Adenoneuroendocrine Carcinomas (MANECs) of the Gastrointestinal Tract: An Update.

Authors:  Stefano La Rosa; Alessandro Marando; Fausto Sessa; Carlo Capella
Journal:  Cancers (Basel)       Date:  2012-01-16       Impact factor: 6.639

8.  Small cell carcinoma of the rectum: A report of imaging results from four cases.

Authors:  Jian Zhou; Jingxian Shen; Huali Ma; Yun Zhang; Meili Sun; Lie Zheng; Yanchun Lv
Journal:  Oncol Lett       Date:  2016-01-20       Impact factor: 2.967
  8 in total

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