Literature DB >> 6101308

Identification of carcinoembryonic antigen in the C-cell of the normal thyroid.

T Kodama, M Fujino, Y Endo, T Obara, Y Fujimoto, T Oda, T Wada.   

Abstract

Carcinoembryonic antigen (CEA) activity was confirmed in the C-cell of the normal thyroid by immunohistochemical techniques. This suggests that CEA production in medullary carcinoma of the thyroid is not initiated by carcinogenesis, but reflects a function of the normal C-cell. It is not yet clear whether CEA production in the C-cell may be influenced by carcinogenesis. The C-cell is the first APUD cell that was confirmed to have CEA activity.

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Year:  1980        PMID: 6101308     DOI: 10.1002/1097-0142(19800101)45:1<98::aid-cncr2820450117>3.0.co;2-c

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  4 in total

Review 1.  The utility of some modern techniques in understanding thyroid pathology.

Authors:  Virginia A LiVoisi
Journal:  Endocr Pathol       Date:  1990-06       Impact factor: 3.943

2.  Human medullary thyroid carcinoma in tissue culture; secretion of calcitonin and carcinoembryonic antigen.

Authors:  R Oosterom; T Verleun; H A Bruining; W H Hackeng; S W Lamberts
Journal:  J Endocrinol Invest       Date:  1987-04       Impact factor: 4.256

3.  Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells.

Authors:  I Damjanov; P S Amenta; F T Bosman
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1983

4.  Immunohistochemical detection of carcinoembryonic antigen (CEA) in parotid gland carcinomas. Analysis of 52 cases.

Authors:  J Caselitz; T Jaup; G Seifert
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1981
  4 in total

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