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Literature DB >> 7821094

Carcinomas of the colon with multidirectional differentiation. Report of two cases and review of the literature.

P Novello¹, P Duvillard, S Grandjouan, D Elias, P Rougier, C Bognel, M Prade.

Abstract

Two cases of colonic carcinomas with multidirectional differentiation are presented. Both tumors showed light microscopic and immunohistochemical evidence of areas of adenocarcinomatous, squamous cell carcinomatous, and neuroendocrine differentiation. Only six similar cases have been previously reported. These highly malignant tumors support the recent concept of a multipotential stem cell within the mucosa of the gastrointestinal tract capable of differentiation in several directions.

Entities: Disease

Mesh：

Year: 1995 PMID： 7821094 DOI： 10.1007/bf02063950

Source DB: PubMed Journal: Dig Dis Sci ISSN： 0163-2116 Impact factor: 3.199

51 in total

1. Stem cell carcinoma of the colon and rectum. Report of two cases and review of the literature.

Authors: D H Palvio; F B Sørensen; M Kløve-Mogensen
Journal: Dis Colon Rectum Date: 1985-06 Impact factor: 4.585

2. Renewal of the epithelium in the descending colon of the mouse. II. Renewal of argentaffin cells.

Authors: W W Chang; C P Leblond
Journal: Am J Anat Date: 1971-05

3. Renewal of the epithelium in the descending colon of the mouse. I. Presence of three cell populations: vacuolated-columnar, mucous and argentaffin.

Authors: W W Chang; C P Leblond
Journal: Am J Anat Date: 1971-05

Carcinomas of the colon with multidirectional differentiation. Report of two cases and review of the literature.

1. Stem cell carcinoma of the colon and rectum. Report of two cases and review of the literature.

2. Renewal of the epithelium in the descending colon of the mouse. II. Renewal of argentaffin cells.

3. Renewal of the epithelium in the descending colon of the mouse. I. Presence of three cell populations: vacuolated-columnar, mucous and argentaffin.

4. Observations on the composition of certain colonic tumors.

5. Primary squamous cell carcinoma and adenocanthoma of the colon.

6. Adenocarcinoid, a mucin-producing carcinoid tumor of the appendix: a study of 39 cases.

7. Adenocarcinoid tumor of the colon arising in preexisting ulcerative colitis.

8. Gastric carcinoid and gastric carcinoma. Morphologic correlates of survival.

9. The endodermal origin of the endocrine cells of an adenocarcinoma of the colon of the rat.

10. Morules in epithelial tumors of the colon and rectum.

1. Fetal and neoplastic expression of the neurotensin gene in the human colon.

2. Composite tumor of the esophagus with tripartite differentiation.

3. Expression of a marker for colonic crypt base cells is correlated with poor prognosis in human colorectal cancer.