Literature DB >> 6188865

Inhibition of a common human anti-hepatitis B surface antigen idiotype by a cyclic synthetic peptide.

R C Kennedy, G R Dreesman, J T Sparrow, A R Culwell, Y Sanchez, I Ionescu-Matiu, F B Hollinger, J L Melnick.   

Abstract

A common human anti-hepatitis B surface antigen idiotype-anti-idiotype reaction was partially inhibited by a cyclic synthetic hepatitis B surface antigen peptide. Reduction of the intrachain disulfide bond and subsequent alkylation destroyed its inhibitory activity, suggesting that a conformation-dependent group alpha epitope was associated with this cyclic peptide.

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Year:  1983        PMID： 6188865      PMCID： PMC255172     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Alteration of hepatitis B antigen (HB Ag) determinants by reduction and alkylation.

Authors:  G R Dreesman; F B Hollinger; R M McCombs; J L Melnick
Journal:  J Gen Virol       Date:  1973-04       Impact factor: 3.891

2.  Reduction and reoxidation of Australia antigen: loss and reconstitution of particle structure and antigenicity.

Authors:  N Sukeno; R Shirachi; J Yamaguchi; N Ishida
Journal:  J Virol       Date:  1972-01       Impact factor: 5.103

3.  Biology of hepatitis B virus.

Authors:  P Tiollais; P Charnay; G N Vyas
Journal:  Science       Date:  1981-07-24       Impact factor: 47.728

4.  Isolation and characterization of the major protein and glycoprotein of hepatitis B surface antigen.

Authors:  D L Peterson
Journal:  J Biol Chem       Date:  1981-07-10       Impact factor: 5.157

Review 5.  Approaching the control of viral hepatitis type B.

Authors:  J L Melnick; G R Dreesman; F B Hollinger
Journal:  J Infect Dis       Date:  1976-02       Impact factor: 5.226

Review 6.  Antigenic structure of myoglobin: the complete immunochemical anatomy of a protein and conclusions relating to antigenic structures of proteins.

Authors:  M Z Atassi
Journal:  Immunochemistry       Date:  1975-05

7.  Common idiotypic determinant associated with human antibodies to hepatitis B surface antigen.

Authors:  R C Kennedy; G R Dreesman
Journal:  J Immunol       Date:  1983-01       Impact factor: 5.422

8.  Immunization of chimpanzees with hepatitis B virus-derived polypeptides.

Authors:  G R Dreesman; F B Hollinger; Y Sanchez; P Oefinger; J L Melnick
Journal:  Infect Immun       Date:  1981-04       Impact factor: 3.441

Review 9.  Type B hepatitis: a review of current prospects for a safe and effective vaccine.

Authors:  V J McAuliffe; R H Purcell; J L Gerin
Journal:  Rev Infect Dis       Date:  1980 May-Jun

10.  Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector.

Authors:  A M Moriarty; B H Hoyer; J W Shih; J L Gerin; D H Hamer
Journal:  Proc Natl Acad Sci U S A       Date:  1981-04       Impact factor: 11.205
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  3 in total

1.  Expression of immunogenic epitopes of hepatitis B surface antigen with hybrid flagellin proteins by a vaccine strain of Salmonella.

Authors:  J Y Wu; S Newton; A Judd; B Stocker; W S Robinson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

Review 2.  Hepatitis B virus infection. Current concepts of chronicity and immunity.

Authors:  G N Vyas; H E Blum
Journal:  West J Med       Date:  1984-05

3.  Enhancement of the immune response to hepatitis B surface antigen. In vivo administration of antiidiotype induces anti-HBs that expresses a similar idiotype.

Authors:  R C Kennedy; G R Dreesman
Journal:  J Exp Med       Date:  1984-03-01       Impact factor: 14.307
  3 in total

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