Literature DB >> 6184033

Combined interaction of antiherpes substances and interferon beta on the multiplication of herpes simplex virus.

C Janz, R Wigand.   

Abstract

The inhibition of herpes simplex virus type 1 (strain McIntyre) by two anti-herpes substances applied in combination was studied by means of a CPE inhibition method In Vero cell microcultures. The following substances were studied: AraA monophosphate, thymine arabinoside, ethyldeoxyuridine, acycloguanosine (acyclovir). 3-fluorothymidine, phosphonoformic acid. Most substance pairs showed a moderate degree of synergism. Two additive interactions and one case of antagonism was observed. Human fibroblast interferon, combined with the antiherpes substances, showed an additive interaction with AraAMP, but synergism with the others.

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Year:  1982        PMID： 6184033     DOI： 10.1007/bf01314722

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  28 in total

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Authors:  G A Gentry; J F Aswell
Journal:  Virology       Date:  1975-05       Impact factor: 3.616

2.  Anti-herpesvirus polychemotherapy.

Authors:  K K Gauri
Journal:  Adv Ophthalmol       Date:  1979

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Authors:  M Fiala; A W Chow; K Miyasaki; L B Guze
Journal:  J Infect Dis       Date:  1974-01       Impact factor: 5.226

4.  In vivo studies with antiviral agents.

Authors:  H E Kaufmann
Journal:  Ann N Y Acad Sci       Date:  1965-07-30       Impact factor: 5.691

5.  Combined antiviral effect of DNA inhibitors on Herpes simplex virus multiplication.

Authors:  R Wigand; M Hassinger
Journal:  Med Microbiol Immunol       Date:  1980       Impact factor: 3.402

Review 6.  Antiviral agents as adjuncts in cancer chemotherapy.

Authors:  W M Shannon; F M Schabel
Journal:  Pharmacol Ther       Date:  1980       Impact factor: 12.310

7.  Synergistic antiviral effects of adenine arabinoside and humoral antibodies in experimental encephalitis due to Herpesvirus hominis.

Authors:  C T Cho; K K Feng; N Brahmacupta
Journal:  J Infect Dis       Date:  1976-02       Impact factor: 5.226

8.  Combined antiviral effect of interferon and acyclovir on herpes simplex virus types 1 and 2.

Authors:  T L Stanwick; R F Schinazi; D E Campbell; A J Nahmias
Journal:  Antimicrob Agents Chemother       Date:  1981-04       Impact factor: 5.191

9.  In vitro and in vivo resistance of herpes simplex virus to 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine).

Authors:  K O Smith; W L Kennell; R H Poirier; F T Lynd
Journal:  Antimicrob Agents Chemother       Date:  1980-02       Impact factor: 5.191

10.  Characteristics of herpesvirus mutants resistant to phosphonoformate and phosphonoacetate.

Authors:  B Eriksson; B Oberg
Journal:  Antimicrob Agents Chemother       Date:  1979-06       Impact factor: 5.191
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  8 in total

1.  Effects of 2,2'-O-cyclocytidine and acyclovir on latent herpes simplex virus in trigeminal ganglia of mice.

Authors:  W G Liu; Z J Chen; J Z Song; Z X Ma
Journal:  Antimicrob Agents Chemother       Date:  1986-02       Impact factor: 5.191

2.  Synergistic effect of human leukocyte interferon and nonoxynol 9 against herpes simplex virus type 2.

Authors:  F Rapp; H Wrzos
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191

3.  Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses.

Authors:  M N Ellis; D C Lobe; T Spector
Journal:  Antimicrob Agents Chemother       Date:  1989-10       Impact factor: 5.191

4.  Acyclovir monotherapy versus acyclovir plus beta-interferon in focal viral encephalitis in children.

Authors:  U Wintergerst; B H Belohradsky
Journal:  Infection       Date:  1992 Jul-Aug       Impact factor: 3.553

5.  Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with beta-interferon against herpes simplex virus type 2 in mice.

Authors:  E B Fraser-Smith; D A Eppstein; Y V Marsh; T R Matthews
Journal:  Antimicrob Agents Chemother       Date:  1984-05       Impact factor: 5.191

6.  Cutaneous herpes simplex virus infection of the guinea pig: lack of resistance to acyclovir and phosphonoformic acid after topical treatment.

Authors:  A Poryo; R Wigand
Journal:  Med Microbiol Immunol       Date:  1984       Impact factor: 3.402

7.  Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with alpha-interferon against herpes simplex virus type 2 in mice.

Authors:  E B Fraser-Smith; D A Eppstein; Y V Marsh; T R Matthews
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

8.  Antiviral effects of bovine interferons on bovine respiratory tract viruses.

Authors:  R W Fulton; M M Downing; J M Cummins
Journal:  J Clin Microbiol       Date:  1984-04       Impact factor: 5.948
  8 in total

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