Literature DB >> 6174945

A novel rearrangement of the human beta-like globin gene cluster.

R J Trent, D K Bowden, J M Old, J S Wainscoat, J B Clegg, D J Weatherall.   

Abstract

The first example of a duplication involving the human beta-like globin genes has been characterised in DNA from a native of Vanuatu. Restriction endonuclease mapping has shown that a 5 kb insert of DNA in the gamma-delta-beta gene cluster is due to duplication of the Ggamma-globin gene and results in a new rearrangement 5'-epsilon-Ggamma-Ggamma-Agamma-delta-beta-3'.

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Year:  1981        PMID： 6174945      PMCID： PMC327636          DOI： 10.1093/nar/9.24.6723

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  21 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Enhanced autoradiographic detection of 32P and 125I using intensifying screens and hypersensitized film.

Authors:  R A Laskey; A D Mills
Journal:  FEBS Lett       Date:  1977-10-15       Impact factor: 4.124

3.  Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: direct determination of gene linkage and intergene distance.

Authors:  R A Flavell; J M Kooter; E De Boer; P F Little; R Williamson
Journal:  Cell       Date:  1978-09       Impact factor: 41.582

4.  Structure of the human fetal globin gene locus.

Authors:  P F Little; R A Flavell; J M Kooter; G Annison; R Williamson
Journal:  Nature       Date:  1979-03-15       Impact factor: 49.962

5.  Isolation of high-molecular-weight DNA from mammalian cells.

Authors:  M Gross-Bellard; P Oudet; P Chambon
Journal:  Eur J Biochem       Date:  1973-07-02

6.  Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

Authors:  Y W Kan; A M Dozy
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

7.  The molecular basis of alpha-thalassemias: frequent occurrence of dysfunctional alpha loci among non-Asians with Hb H disease.

Authors:  S H Orkin; J Old; H Lazarus; C Altay; A Gurgey; D J Weatherall; D G Nathan
Journal:  Cell       Date:  1979-05       Impact factor: 41.582

8.  Characterisation of deletions which affect the expression of fetal globin genes in man.

Authors:  E F Fritsch; R M Lawn; T Maniatis
Journal:  Nature       Date:  1979-06-14       Impact factor: 49.962

9.  Insertion of synthetic copies of human globin genes into bacterial plasmids.

Authors:  J T Wilson; L B Wilson; J K deRiel; L Villa-komaroff; A Efstratiadis; B G Forget; S M Weissman
Journal:  Nucleic Acids Res       Date:  1978-02       Impact factor: 16.971

10.  Nucleotide sequence of the rightward operator of phage lambda.

Authors:  T Maniatis; A Jeffrey; D G Kleid
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205
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  13 in total

1.  A silent deletion in the beta-globin gene cluster.

Authors:  V E Tate; A V Hill; D K Bowden; J R Sadler; D J Weatherall; J B Clegg
Journal:  Nucleic Acids Res       Date:  1986-06-25       Impact factor: 16.971

2.  Globin genes in Micronesia: origins and affinities of Pacific Island peoples.

Authors:  D F O'Shaughnessy; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025

3.  A new epsilon globin HincII variant fragment length in a South African Negroid family.

Authors:  M Ramsay; J A Thomson; T Jenkins
Journal:  J Med Genet       Date:  1986-04       Impact factor: 6.318

4.  Different hematologic phenotypes are associated with the leftward (-alpha 4.2) and rightward (-alpha 3.7) alpha+-thalassemia deletions.

Authors:  D K Bowden; A V Hill; D R Higgs; S J Oppenheimer; D J Weatherall; J B Clegg
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

5.  Globin genes in Polynesians have many rearrangements including a recently described gamma gamma gamma gamma/.

Authors:  R J Trent; K N Mickleson; T Wilkinson; J Yakas; M W Dixon; P J Hill; H Kronenberg
Journal:  Am J Hum Genet       Date:  1986-09       Impact factor: 11.025

Review 6.  The evolution of the alpha- and beta-globin gene clusters in human populations.

Authors:  A V Hill; J S Wainscoat
Journal:  Hum Genet       Date:  1986-09       Impact factor: 4.132

7.  Globin genes are useful markers to identify genetic similarities between Fijians and Pacific Islanders from Polynesia and Melanesia.

Authors:  R J Trent; J G Buchanan; A Webb; R P Goundar; L M Seruvatu; K N Mickleson
Journal:  Am J Hum Genet       Date:  1988-04       Impact factor: 11.025

Review 8.  The thalassemias: molecular mechanisms of human genetic disease.

Authors:  R A Spritz; B G Forget
Journal:  Am J Hum Genet       Date:  1983-05       Impact factor: 11.025

9.  Gamma thalassemia resulting from the deletion of a gamma-globin gene.

Authors:  P K Sukumaran; T Nakatsuji; M B Gardiner; A L Reese; J G Gilman; T H Huisman
Journal:  Nucleic Acids Res       Date:  1983-07-11       Impact factor: 16.971

10.  Abnormal arrangements in the alpha- and gamma-globin gene clusters in a relatively large group of Japanese newborns.

Authors:  K Shimizu; T Harano; K Harano; S Miwa; Y Amenomori; Y Ohba; F Kutlar; T H Huisman
Journal:  Am J Hum Genet       Date:  1986-01       Impact factor: 11.025
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