Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Acute turpentine inflammation and kinin release in rat-paw thermic oedema.

Literature DB >> 6173056

Acute turpentine inflammation and kinin release in rat-paw thermic oedema.

E A Limãos, D R Borges, J C Souza-Pinto, A H Gordon, J L Prado.

Abstract

Livers from rats at 2-3 days after s.c. injection of turpentine, when perfused, synthesized prekallikrein nearly 3 times faster than did livers from normal rats. On the other hand paw oedema, produced by heating to 46 degrees, in rats injured in this way was less marked. Likewise in such rats the amount of bradykinin release by 50 min. of coaxial perfusion of the paw was only 13.6 +/- 4.6 compared with 63.1 +/- 13.4 ng in normal rats. A possible explanation for the observed reduction in production of bradykinin may be inhibition of kallikrein due to an increased concentration of alpha 2-macroglobulin.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1981 PMID： 6173056 PMCID： PMC2041726

Source DB: PubMed Journal: Br J Exp Pathol ISSN： 0007-1021

13 in total

1. Anti-inflammatory properties of lyophilized inflammatory exudates.

Authors: G DIPASQUALE; R J GIRERD
Journal: Am J Physiol Date: 1961-12

2. Release of bradykinin and the mechanism of production of a "thermic edema (45 degrees C)" in the rat's paw.

Authors: M ROCHA E SILVA; A ANTONIO
Journal: Med Exp Int J Exp Med Date: 1960

3. Rapid foot volume measurements on unanesthetized rats, and the question of a phenylbutazone effect on anaphylactoid edema.

Authors: C V WINDER; J WAX; M A BEEN
Journal: Arch Int Pharmacodyn Ther Date: 1957-10-01

4. Recovery of an anti-inflammatory fraction from inflammatory exudate.

Authors: T H RINDANI
Journal: Indian J Med Res Date: 1956-10 Impact factor: 2.375

5. Kininogen and kininogenase synthesis by the liver of normal and injured rats.

Authors: D R Borges; A H Gordon
Journal: J Pharm Pharmacol Date: 1976-01 Impact factor: 3.765

6. Inhibitory effect of foetal alpha 2 globulin, an acute phase protein, on carrageenin oedema in the rat.

Authors: J van Gool; J Schreuder; N C Ladiges
Journal: J Pathol Date: 1974-04 Impact factor: 7.996

7. Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors: G Mancini; A O Carbonara; J F Heremans
Journal: Immunochemistry Date: 1965-09

8. Anti-inflammatory properties of human inflammatory exudate.

Authors: E J Billingham; B V Robinson; J M Robson
Journal: Br Med J Date: 1969-04-12

9. Effects of injury on the concentration of alpha1-macroglobulin and alpha2-macroglobulin in the plasmas of male and remale rats.

Authors: A G Bosanquet; A M Chandler; A H Gordon
Journal: Experientia Date: 1976-10-15

Acute turpentine inflammation and kinin release in rat-paw thermic oedema.

1. Anti-inflammatory properties of lyophilized inflammatory exudates.

2. Release of bradykinin and the mechanism of production of a "thermic edema (45 degrees C)" in the rat's paw.

3. Rapid foot volume measurements on unanesthetized rats, and the question of a phenylbutazone effect on anaphylactoid edema.

4. Recovery of an anti-inflammatory fraction from inflammatory exudate.

5. Kininogen and kininogenase synthesis by the liver of normal and injured rats.

6. Inhibitory effect of foetal alpha 2 globulin, an acute phase protein, on carrageenin oedema in the rat.

7. Immunochemical quantitation of antigens by single radial immunodiffusion.

8. Anti-inflammatory properties of human inflammatory exudate.

9. Effects of injury on the concentration of alpha1-macroglobulin and alpha2-macroglobulin in the plasmas of male and remale rats.

10. Synthesis of prekallikrein and metabolism of plasma kallikrein by perfused rat liver.

1. The clearance rate of plasma kallikrein by the liver increases during the acute-phase response to inflammation.

2. The role of nuclei, polyribosomes and cytosol factors in the onset of the acute-phase reaction in the liver cell.

3. Further studies of the mechanism of counter irritation by turpentine.

4. Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients.