Literature DB >> 5775457

Anti-inflammatory properties of human inflammatory exudate.

E J Billingham, B V Robinson, J M Robson.   

Abstract

An inflammatory exudate collected from a site of major surgery (partial gastrectomy) was found to possess definite anti-inflammatory properties when tested by the carrageenin oedema technique (a method widely adopted for the assessment of potential anti-rheumatic agents). Such anti-inflammatory properties could not be detected in the serum of normal healthy adults or in an abdominal asdtes fluid. The active component in the exudate showed several properties in common with a similar anti-inflammatory substance present in inflammatory exudates of animal origin.

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Year:  1969        PMID: 5775457      PMCID: PMC1982859          DOI: 10.1136/bmj.2.5649.93

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  6 in total

1.  PRODUCTION OF AN ANTI-INFLAMMATORY SUBSTANCE AT A SITE OF INFLAMMATION.

Authors:  B V ROBINSON; J M ROBSON
Journal:  Br J Pharmacol Chemother       Date:  1964-10

2.  ANTIPHLOGISTIC ACTION OF GRANULOMA POUCH EXUDATES IN INTACT OR ADRENALECTOMIZED RATS.

Authors:  G DIPASQUALE; R J GIRERD; V L BEACH; B G STEINETZ
Journal:  Am J Physiol       Date:  1963-12

3.  Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.

Authors:  C A WINTER; E A RISLEY; G W NUSS
Journal:  Proc Soc Exp Biol Med       Date:  1962-12

4.  Anti-inflammatory properties of lyophilized inflammatory exudates.

Authors:  G DIPASQUALE; R J GIRERD
Journal:  Am J Physiol       Date:  1961-12

5.  Serum protein changes after gastrectomy as a model of acute phase reaction.

Authors:  M Werner; D Odenthal
Journal:  J Lab Clin Med       Date:  1967-08

6.  Further studies on the anti-inflammatory factor found at a site of inflammation.

Authors:  B V Robinson; J M Robson
Journal:  Br J Pharmacol Chemother       Date:  1966-02
  6 in total
  9 in total

1.  Autoimmune bowel disease.

Authors:  F H Anderson
Journal:  Can Fam Physician       Date:  1979-03       Impact factor: 3.275

2.  Inflamed-tissue factor(s): an autoregulatory mechanism of some acute inflammatory responses.

Authors:  I L Bonta; J Noordhoek
Journal:  Experientia       Date:  1974-04-15

3.  Effect of pregnancy serum on experimental inflammation.

Authors:  R H Persellin; S E Vance; A Peery
Journal:  Br J Exp Pathol       Date:  1974-02

4.  Separation of irritancy from the anti-inflammatory component of inflammation exudate.

Authors:  M E Billingham; B V Robinson
Journal:  Br J Pharmacol       Date:  1972-02       Impact factor: 8.739

5.  Anti-inflammatory mechanism of inflamed-tissue factor.

Authors:  I L Bonta; J Noordhoek
Journal:  Agents Actions       Date:  1973-12

Review 6.  The anti-inflammatory activity of irritants.

Authors:  D C Atkinson; R Hicks
Journal:  Agents Actions       Date:  1975-08

7.  Stimulation of the hypothalamo-pituitary-adrenal axis by compounds formed in inflamed tissue.

Authors:  J G Leme; E E Schapoval
Journal:  Br J Pharmacol       Date:  1975-01       Impact factor: 8.739

8.  The role of bacterial contamination in the isolation of apparent anti-inflammatory factors from rabbit anti-lymphocytic serum.

Authors:  E D Maguire; R B Wallis
Journal:  Br J Pharmacol       Date:  1977-02       Impact factor: 8.739

9.  Acute turpentine inflammation and kinin release in rat-paw thermic oedema.

Authors:  E A Limãos; D R Borges; J C Souza-Pinto; A H Gordon; J L Prado
Journal:  Br J Exp Pathol       Date:  1981-12
  9 in total

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