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Literature DB >> 1456171

The clearance rate of plasma kallikrein by the liver increases during the acute-phase response to inflammation.

B Martins¹, M Kouyoumdjian, E A Limaos, D R Borges.

Abstract

The effect of the acute-phase response on the clearance rate of plasma kallikrein by the exsanguinated liver was studied in three groups of rats: a control group and two other groups that received either turpentine or an endogenous pyrogen preparation. The plasma kallikrein clearance rates were significantly higher in both inflamed groups.

Entities: Chemical Disease Gene Species

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Year: 1992 PMID： 1456171 DOI： 10.1007/bf01987898

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

14 in total

1. Effect of endogenous pyrogen, corticosteroids and inhibitors of prostaglandins and leukotrienes on the plasma concentrations of haptoglobin and fibrinogen in rats.

Authors: E A Limãos; E B Ribeiro; A H Gordon
Journal: Braz J Med Biol Res Date: 1985 Impact factor: 2.590

2. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

Authors: J Gauldie; C Richards; D Harnish; P Lansdorp; H Baumann
Journal: Proc Natl Acad Sci U S A Date: 1987-10 Impact factor: 11.205

The clearance rate of plasma kallikrein by the liver increases during the acute-phase response to inflammation.

1. Effect of endogenous pyrogen, corticosteroids and inhibitors of prostaglandins and leukotrienes on the plasma concentrations of haptoglobin and fibrinogen in rats.

2. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

3. Kininogen and kininogenase synthesis by the liver of normal and injured rats.

4. The liver is the main organ to clear plasma and tissue kallikreins from rat plasma, in vivo.

5. Effect of leukocytic endogenous mediator on plasma fibrinogen and haptoglobin.

6. Characterization of a kinin-converting arylaminopeptidase from human liver.

7. Synthesis of prekallikrein and metabolism of plasma kallikrein by perfused rat liver.

8. Plasma kallikrein clearance by the liver of normal and injured rats.

9. Rat plasma kallikrein clearance by perfused rat liver.

10. Kinin-inactivating endopeptidase from rat liver.

1. The contact system proteases play disparate roles in streptococcal sepsis.