Literature DB >> 6173016

Activity of di-beta-lysyl-capreomycin IIA and palmitoyl tuberactinamine N against drug-resistant mutants with altered ribosomes.

T Yamada, T Teshima, T Shiba.   

Abstract

The effects of 61 synthetic tuberactinomycin derivatives on polypeptide synthesis were tested in bacterial cell-free systems. Di-beta-lys-capreomycin IIA was more effective than the natural product. Palmitoyl tuberactinamine N inhibited the growth of tuberactinomycin-resistant mutants and was not a ribosome inhibitor.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6173016      PMCID： PMC181807          DOI： 10.1128/AAC.20.6.834

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Altered ribosomes in antibiotic-resistant mutants of Mycobacterium smegmatis.

Authors:  T Yamada; K Masuda; Y Mizuguchi; K Suga
Journal:  Antimicrob Agents Chemother       Date:  1976-05       Impact factor: 5.191

2.  Dual actions of viomycin on the ribosomal functions.

Authors:  Y F Liou; N Tanaka
Journal:  Biochem Biophys Res Commun       Date:  1976-07-26       Impact factor: 3.575

3.  The inhibition of ribosomal translocation by viomycin.

Authors:  J Modolell
Journal:  Eur J Biochem       Date:  1977-12

4.  Mapping of antibiotic resistance markers in Mycobacterium smegmatis.

Authors:  K Suga; Y Mizuguchi
Journal:  Jpn J Microbiol       Date:  1974-03

5.  Misreading of RNA codewords induced by aminoglycoside antibiotics.

Authors:  J Davies; L Gorini; B D Davis
Journal:  Mol Pharmacol       Date:  1965-07       Impact factor: 4.436

6.  Genetic and biochemical studies on drug-resistant mutants in Mycobacterium smegmatis.

Authors:  Y Mizuguchi; K Suga; K Masuda; T Yamada
Journal:  Jpn J Microbiol       Date:  1974-11

7.  Chemical studies on tuberactinomycin. XIII. Modification of beta-ureidodehydroalanine residue in tuberactinomycin N.

Authors:  S Nomoto; T Shiba
Journal:  J Antibiot (Tokyo)       Date:  1977-11       Impact factor: 2.649

8.  Analysis of ribosomes from viomycin-sensitive and -resistant strains of Mycobacterium smegmatis.

Authors:  T Yamada; K Masuda; K Shoji; M Hori
Journal:  J Bacteriol       Date:  1972-10       Impact factor: 3.490

9.  Chemical studies on tuberactinomycin. 3. The chemical structure of viomycin (tuberactinomycin B).

Authors:  T Noda; T Take; A Nagata; T Wakamiya; T Shiba
Journal:  J Antibiot (Tokyo)       Date:  1972-07       Impact factor: 2.649

10.  The revised structure of capreomycin.

Authors:  S Nomoto; T Teshima; T Wakamiya; T Shiba
Journal:  J Antibiot (Tokyo)       Date:  1977-11       Impact factor: 2.649
View more
  1 in total

1.  The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.

Authors:  Robin E Stanley; Gregor Blaha; Robert L Grodzicki; Michael D Strickler; Thomas A Steitz
Journal:  Nat Struct Mol Biol       Date:  2010-02-14       Impact factor: 15.369
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.