| Literature DB >> 6169997 |
R A Hitzeman, F E Hagie, H L Levine, D V Goeddel, G Ammerer, B D Hall.
Abstract
A DNA sequence coding for mature human leukocyte interferon D (LeIF-D) was linked with DNA fragments of the 5'-flanking sequences of the Saccharomyces cerevisiae (yeast) alcohol dehydrogenase I gene in a plasmid capable of autonomous replication and selection in both yeast and Escherichia coli. Yeast cells transformed by these plasmids synthesize up to 1 x 10(6) molecules of biologically active LeIF-D per cell.Entities:
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Year: 1981 PMID: 6169997 DOI: 10.1038/293717a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962