Literature DB >> 6167453

Interferon enhances the amount of membrane-bound beta2-microglobulin and its release from human Burkitt cells.

M Fellous, R Bono, F Hyafil, I Gresser.   

Abstract

Human leukocytes interferon (HuIFN-A) increased the amount of beta2-microglobulin on the surface of human Burkitt lymphoma cells (Ramos) and also increased the amount released into the culture medium. The effect was observed 1 h after addition of IFN. These results suggest that the increase in beta2-microglobulin on the cell surface of IFN-treated cells is not due to a decreased shedding of antigen from the cell surface, nor an "unmasking" of surface antigen, but rather to an increased synthesis of antigen.

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Year:  1981        PMID： 6167453     DOI： 10.1002/eji.1830110616

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  10 in total

1.  Therapeutic monoclonal antibodies for multiple myeloma: an update and future perspectives.

Authors:  Jing Yang; Qing Yi
Journal:  Am J Blood Res       Date:  2011-06-15

Review 2.  IFN-induced modulation of histocompatibility antigens on human cells. Background, mechanisms and perspectives.

Authors:  M Hokland; P Basse; J Justesen; P Hokland
Journal:  Cancer Metastasis Rev       Date:  1988-11       Impact factor: 9.264

3.  Interferon increases HLA synthesis in melanoma cells: interferon-resistant and -sensitive cell lines.

Authors:  T Y Basham; M F Bourgeade; A A Creasey; T C Merigan
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

4.  Receptor mediated pathways for interferon action: in vivo implications.

Authors:  K E Mogensen; M T Bandu; F Vignaux; G Uze; P Eid
Journal:  Med Oncol Tumor Pharmacother       Date:  1984

5.  Human interferon-gamma enhances the expression of class I and class II major histocompatibility complex products in neoplastic cells more effectively than interferon-alpha and interferon-beta.

Authors:  A Dolei; M R Capobianchi; F Ameglio
Journal:  Infect Immun       Date:  1983-04       Impact factor: 3.441

Review 6.  The antitumor effects of interferon.

Authors:  I Gresser
Journal:  Med Oncol Tumor Pharmacother       Date:  1986

7.  The beta2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon.

Authors:  F Rosa; H Berissi; J Weissenbach; L Maroteaux; M Fellous; M Revel
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

8.  Recombinant gamma interferon provokes resistance of human breast cancer cells to spontaneous and IL-2 activated non-MHC restricted cytotoxicity.

Authors:  N Jabrane-Ferrat; F Calvo; A Faille; J F Lagabrielle; N Boisson; A Quillet; D Fradelizi
Journal:  Br J Cancer       Date:  1990-04       Impact factor: 7.640

9.  Control of HLA-A,B,C synthesis and expression in interferon-treated cells.

Authors:  O R Burrone; C Milstein
Journal:  EMBO J       Date:  1982       Impact factor: 11.598

10.  Stimulation of HLA-A,B,C by IFN-alpha. The derivation of Molt 4 variants and the differential expression of HLA-A,B,C subsets.

Authors:  O R Burrone; R F Kefford; D Gilmore; C Milstein
Journal:  EMBO J       Date:  1985-11       Impact factor: 11.598
  10 in total

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