Literature DB >> 6166531

Gc revisited: six further Gc-phenotypes delineated by isoelectric focusing and by polyacrylamide gel electrophoresis.

H Cleve, J Constans, S Berg, B Hoste, G Ishimoto, H Matsumoto, E K Spees, W Weber.   

Abstract

Six newly observed Gc variants are described. The variants Gc 1A10, 1A11, 1A12, 1A13, and 1C11 have double band patterns. The anodal bands of these variants are susceptible to neuraminidase treatment. Gc 2A7 is a single band variant which is not altered by neuraminidase incubation. Polyacrylamide gel isoelectrofocusing with immunofixation and polyarcylamide gel electrophoresis appear to be efficient methods for the analysis of the Gc system.

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Year:  1981        PMID： 6166531     DOI： 10.1007/BF00278951

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  9 in total

1.  TWO GENETIC VARIANTS OF THE GROUP-SPECIFIC COMPONENT OF HUMAN SERUM: GC CHIPPEWA AND GC ABORIGINE.

Authors:  H CLEVE; R L KIRK; W C PARKER; A G BEARN; L E SCHACHT; H KLEINMAN; W R HORSFALL
Journal:  Am J Hum Genet       Date:  1963-12       Impact factor: 11.025

2.  Molecular basis for the three major forms of human serum vitamin D binding protein (group-specific component).

Authors:  J Svasti; A Kurosky; A Bennett; B H Bowman
Journal:  Biochemistry       Date:  1979-04-17       Impact factor: 3.162

3.  A new variant phenotype of the group-specific component (Gc) found in a Japanese family.

Authors:  K Omoto; H Cleve; S Misawa
Journal:  Jinrui Idengaku Zasshi       Date:  1972-09

4.  Group-specific component (Gc) polymorphism in Japanese: an analysis by isoelectric focusing on polyacrylamide gels.

Authors:  G Ishimoto; M Kuwata; H Nakajima
Journal:  Jinrui Idengaku Zasshi       Date:  1979-06

5.  The distribution of the group-specific component (Gc) subtypes in Japanese.

Authors:  K Omoto; K Miyake
Journal:  Jinrui Idengaku Zasshi       Date:  1978-06

6.  Group-specific component: evidence for two subtypes of the Gc1 gene.

Authors:  J Constans; M Viau
Journal:  Science       Date:  1977-12-09       Impact factor: 47.728

7.  Analysis of the Gc polymorphism in human populations by isoelectrofocusing on polyacrylamide gels. Demonstration of subtypes of the Gc allele and of additional Gc variants.

Authors:  J Constans; M Viau; H Cleve; G Jaeger; J C Quilici; M J Palisson
Journal:  Hum Genet       Date:  1978-02-23       Impact factor: 4.132

8.  Population genetic studies of the Philippine Negritos. I. A pilot survey of red cell enzyme and serum protein groups.

Authors:  K Omoto; S Misawa; S Harada; J S Sumpaico; P M Medado; H Ogonuki
Journal:  Am J Hum Genet       Date:  1978-03       Impact factor: 11.025

9.  Neuraminidase treatment reveals sialic acid differences in certain genetic variants of the Gc system (vitamin-D-binding protein).

Authors:  H Cleve; W Patutschnick
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132
  9 in total
  11 in total

1.  A hereditary double double-banded variation in the vitamin D-binding protein (GC) system analyzed by immunoblotting: duplication of the 1F and 1A2 genes?

Authors:  T Yasuda; Y Ikehara; S Takagi; K Mizuta; K Kishi
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

2.  Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids.

Authors:  P S Henthorn; B J Knoll; M Raducha; K N Rothblum; C Slaughter; M Weiss; M A Lafferty; T Fischer; H Harris
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

Review 3.  Ethnic variation in vitamin D-binding protein (GC): a review of isoelectric focusing studies in human populations.

Authors:  M I Kamboh; R E Ferrell
Journal:  Hum Genet       Date:  1986-04       Impact factor: 4.132

4.  [Gc subtypes: demonstration using isoelectric focusing. Study of population and formal genetics].

Authors:  D Patzelt; T Nagai; H Schröder; H J Hermann
Journal:  Z Rechtsmed       Date:  1983

5.  Five new Gc variants detected by isoelectric focusing in agarose gel.

Authors:  M Thymann; K Hjalmarsson; M Svensson
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

6.  Gc subtypes determined by ultrathin-layer isoelectric focusing. Distribution in the Veneto population (Italy).

Authors:  P Cortivo; M Biasiolo; L Caenazzo; C Scorretti; P Benciolini; G Ongaro
Journal:  Z Rechtsmed       Date:  1984

7.  The polymorphism of the vitamin D-binding protein (Gc); isoelectric focusing in 3 M urea as additional method for identification of genetic variants.

Authors:  J Constans; H Cleve; D Dykes; M Fischer; R L Kirk; S S Papiha; W Scheffran; R Scherz; M Thymann; W Weber
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

8.  Description of six new Gc variants.

Authors:  D Dykes; B Copouls; H Polesky
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

9.  A new single band variant of the Gc subtypes determined by isoelectric focusing.

Authors:  I Nakasono; M Iwasaki; M Ogata; C Yoshida; T Yoshitake; K Narita; H Suyama; Y Tomohiro
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

10.  A deficiency mutant of the Gc system.

Authors:  B Vavrusa; H Cleve; J Constans
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132
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