Literature DB >> 6179851

Five new Gc variants detected by isoelectric focusing in agarose gel.

M Thymann, K Hjalmarsson, M Svensson.   

Abstract

Five new genetically determined Gc variants were observed by isoelectric focusing. Seven rare variants 1A4, 1Cl, 1C3, 1C9, 1C11, 2A2, and 2A5 were also found in the material comprising Danish and Swedish paternity cases. All the variants were further analysed by electrophoresis in agarose gel. Two of the new variants had double bands of which the anodal one was susceptible to neuraminidase treatment (Gc 1C13 and 1C14). The three other new variants appeared as a single band, which was unaffected by neuraminidase treatment (Gc 2A9, 2C5, and 2C6). The Gc Ar variant originally detected by electrophoresis was reexamined by isoelectric focusing and named 2C4.

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Year:  1982        PMID: 6179851     DOI: 10.1007/BF00569215

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  13 in total

1.  Genetic studies on the Gc subtypes.

Authors:  H Cleve; W Patutschnick; S Nevo; G G Wendt
Journal:  Hum Genet       Date:  1978-10-31       Impact factor: 4.132

2.  Gc Opava: a variant of the group-specific component (Gc) system with an electrophoretic mobility intermediate between Gc 1-1 and Gc 2-2.

Authors:  B Vavrusa; H Cleve
Journal:  Vox Sang       Date:  1974-02       Impact factor: 2.144

3.  The distribution of Gc subtypes among the mongoloid populations.

Authors:  H Matsumoto; K Matsui; N Ishida; K Ohkura; Y S Teng
Journal:  Am J Phys Anthropol       Date:  1980-11       Impact factor: 2.868

4.  Group-specific component. Report on the First International Workshop, Collège de France--July 27-28, 1978--Paris.

Authors:  J Constans; H Cleve
Journal:  Hum Genet       Date:  1979-04-27       Impact factor: 4.132

5.  Gc subtypes demonstrated by isoelectric focusing: further data and description of new variants among an African sample (Fula) from Senegal.

Authors:  J Constans; M Viau; G Pison; A Langaney
Journal:  Jinrui Idengaku Zasshi       Date:  1978-06

6.  Human group-specific component. Changes in electrophoretic mobility resulting from vitamin D binding and from neuraminidase digestion.

Authors:  J Svasti; B H Bowman
Journal:  J Biol Chem       Date:  1978-06-25       Impact factor: 5.157

7.  Group-specific component: evidence for two subtypes of the Gc1 gene.

Authors:  J Constans; M Viau
Journal:  Science       Date:  1977-12-09       Impact factor: 47.728

8.  Gc revisited: six further Gc-phenotypes delineated by isoelectric focusing and by polyacrylamide gel electrophoresis.

Authors:  H Cleve; J Constans; S Berg; B Hoste; G Ishimoto; H Matsumoto; E K Spees; W Weber
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

9.  Neuraminidase treatment reveals sialic acid differences in certain genetic variants of the Gc system (vitamin-D-binding protein).

Authors:  H Cleve; W Patutschnick
Journal:  Hum Genet       Date:  1979-03-12       Impact factor: 4.132

10.  Gc subtypes determined by agarose isoelectrofocusing: distribution in Denmark and application to paternity cases.

Authors:  M Thymann
Journal:  Hum Hered       Date:  1981       Impact factor: 0.444

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  8 in total

Review 1.  Ethnic variation in vitamin D-binding protein (GC): a review of isoelectric focusing studies in human populations.

Authors:  M I Kamboh; R E Ferrell
Journal:  Hum Genet       Date:  1986-04       Impact factor: 4.132

2.  Gc subtypes determined by ultrathin-layer isoelectric focusing. Distribution in the Veneto population (Italy).

Authors:  P Cortivo; M Biasiolo; L Caenazzo; C Scorretti; P Benciolini; G Ongaro
Journal:  Z Rechtsmed       Date:  1984

3.  The polymorphism of the vitamin D-binding protein (Gc); isoelectric focusing in 3 M urea as additional method for identification of genetic variants.

Authors:  J Constans; H Cleve; D Dykes; M Fischer; R L Kirk; S S Papiha; W Scheffran; R Scherz; M Thymann; W Weber
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

4.  Description of six new Gc variants.

Authors:  D Dykes; B Copouls; H Polesky
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

5.  A new single band variant of the Gc subtypes determined by isoelectric focusing.

Authors:  I Nakasono; M Iwasaki; M Ogata; C Yoshida; T Yoshitake; K Narita; H Suyama; Y Tomohiro
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

6.  A deficiency mutant of the Gc system.

Authors:  B Vavrusa; H Cleve; J Constans
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

7.  Gc subtypes identified by isoelectric focusing in baboons (Papio hamadryas).

Authors:  D Dykes; M Crawford; H Polesky
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

8.  Unusual sialilation of three different rare genetic variants of serum DBP: Gc1A17, Gc1A16, and Gc1A11.

Authors:  M Thymann; B Hoste; W Scheffrahn; J Constans; H Cleve
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

  8 in total

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