Literature DB >> 3461452

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids.

P S Henthorn, B J Knoll, M Raducha, K N Rothblum, C Slaughter, M Weiss, M A Lafferty, T Fischer, H Harris.   

Abstract

Amino-terminal amino acid sequences (42 residues) were determined for the products of the three common alleles at the human placental alkaline phosphatase [orthophosphoric-monoester phosphohydrolase (alkaline optimum), EC 3.1.3.1] gene locus. The sequences differ at position 3, which is proline in types 1 and 2 but is leucine in type 3. cDNA libraries were constructed in phage lambda gt11 and used to isolate clones covering the coding regions of types 1 and 3 cDNAs. Comparison of the deduced amino acid sequences of the types 1 and 3 proteins showed 7 differences out of 513 amino acids, each due to a single base substitution. cDNA sequence comparisons showed three silent substitutions in the coding regions and three base differences in the greater than 1 kilobase pairs of 3' untranslated sequences.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3461452      PMCID： PMC386335          DOI： 10.1073/pnas.83.15.5597

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  30 in total

1.  Rare variants of placental alkaline phosphatase.

Authors:  L J Donald; E B Robson
Journal:  Ann Hum Genet       Date:  1974-01       Impact factor: 1.670

2.  The incidence of rare alleles determining electrophoretic variants: data on 43 enzyme loci in man.

Authors:  H Harris; D A Hopkinson; E B Robson
Journal:  Ann Hum Genet       Date:  1974-01       Impact factor: 1.670

3.  Differential inhibition of the products of the human alkaline phosphatase loci.

Authors:  R A Mulivor; L I Plotkin; H Harris
Journal:  Ann Hum Genet       Date:  1978-07       Impact factor: 1.670

4.  Nucleotide sequence of part of the gene for human chorionic somatomammotropin: purification of DNA complementary to predominant mRNA species.

Authors:  P H Seeburg; J Shine; J A Martial; A Ullrich; J D Baxter; H M Goodman
Journal:  Cell       Date:  1977-09       Impact factor: 41.582

5.  The syntheiss of high yields of full-length reverse transcripts of globin mRNA.

Authors:  E Y Friedman; M Rosbash
Journal:  Nucleic Acids Res       Date:  1977-10       Impact factor: 16.971

6.  Further studies on the genetics of placental alkaline phosphatase.

Authors:  E B Robson; H Harris
Journal:  Ann Hum Genet       Date:  1967-01       Impact factor: 1.670

7.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

8.  Molecular cloning and sequence analysis of human placental alkaline phosphatase.

Authors:  J L Millán
Journal:  J Biol Chem       Date:  1986-03-05       Impact factor: 5.157

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.

Authors:  E Weiss; L Golden; R Zakut; A Mellor; K Fahrner; S Kvist; R A Flavell
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
View more
  27 in total

1.  Characterization of the phosphatidylinositol-glycan membrane anchor of human placental alkaline phosphatase.

Authors:  A D Howard; J Berger; L Gerber; P Familletti; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

Review 2.  Interpreting cDNA sequences: some insights from studies on translation.

Authors:  M Kozak
Journal:  Mamm Genome       Date:  1996-08       Impact factor: 2.957

3.  Isolation and characterization of the mouse liver/bone/kidney-type alkaline phosphatase gene.

Authors:  M Terao; M Studer; M Gianní; E Garattini
Journal:  Biochem J       Date:  1990-06-15       Impact factor: 3.857

4.  Homologous recombination between the LTRs of a human retrovirus-like element causes a 5-kb deletion in two siblings.

Authors:  D L Mager; N L Goodchild
Journal:  Am J Hum Genet       Date:  1989-12       Impact factor: 11.025

5.  Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif.

Authors:  S A Liebhaber; J G Emery; M Urbanek; X K Wang; N E Cooke
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

6.  Structure and expression of rat osteosarcoma (ROS 17/2.8) alkaline phosphatase: product of a single copy gene.

Authors:  M A Thiede; K Yoon; E E Golub; M Noda; G A Rodan
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

7.  Human placental and intestinal alkaline phosphatase genes map to 2q34-q37.

Authors:  C A Griffin; M Smith; P S Henthorn; H Harris; M J Weiss; M Raducha; B S Emanuel
Journal:  Am J Hum Genet       Date:  1987-12       Impact factor: 11.025

8.  Expression of active, membrane-bound human placental alkaline phosphatase by transfected simian cells.

Authors:  J Berger; A D Howard; L Gerber; B R Cullen; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

9.  Cloning and characterization of a cDNA coding for mouse placental alkaline phosphatase.

Authors:  M Terao; B Mintz
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

10.  Acid phosphatase-1(1), a tightly linked molecular marker for root-knot nematode resistance in tomato: from protein to gene, using PCR and degenerate primers containing deoxyinosine.

Authors:  J M Aarts; J G Hontelez; P Fischer; R Verkerk; A van Kammen; P Zabel
Journal:  Plant Mol Biol       Date:  1991-04       Impact factor: 4.076
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.