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Literature DB >> 6159637

Amino-terminal amino acid sequence of human leukocyte interferon.

W P Levy, J Shively, M Rubinstein, U Del Valle, S Pestka.

Abstract

We report the amino-terminal sequence of the first 22 amino acids of human leukocyte interferon. These and other results indicate that human leukocyte interferon consists of many individual species. We, therefore, postulate that diversity in this protein is routinely present and that the human leukocyte interferons represent a multigene family.

Entities: Species

Mesh：

Substances：

Year: 1980 PMID： 6159637 PMCID： PMC350004 DOI： 10.1073/pnas.77.9.5102

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

13 in total

1. Improved manual sequencing methods.

Authors: G E Tarr
Journal: Methods Enzymol Date: 1977 Impact factor: 1.600

2. Amino acid sequence studies on ten ribosomal proteins of Escherichia coli with an improved sequenator equipped with an automatic conversion device.

Authors: B Wittmann-Liebold
Journal: Hoppe Seylers Z Physiol Chem Date: 1973 Oct-Nov

3. Rapid analysis of amino acid phenylthiohydantoins by high-performance liquid chromatography.

Authors: C L Zimmerman; E Appella; J J Pisano
Journal: Anal Biochem Date: 1977-02 Impact factor: 3.365

4. A device coupled to a modified sequenator for the automated conversion of anilinothiazolinones into PTH amino acids.

Authors: B Wittmann-Liebold; H Graffunder; H Kohls
Journal: Anal Biochem Date: 1976-10 Impact factor: 3.365

5. New protein sequenator with increased sensitivity.

Authors: M W Hunkapiller; L E Hood
Journal: Science Date: 1980-02-01 Impact factor: 47.728

6. Human leukocyte interferon: production, purification to homogeneity, and initial characterization.

Authors: M Rubinstein; S Rubinstein; P C Familletti; R S Miller; A A Waldman; S Pestka
Journal: Proc Natl Acad Sci U S A Date: 1979-02 Impact factor: 11.205

7. Human leukocyte interferon purified to homogeneity.

Authors: M Rubinstein; S Rubinstein; P C Familletti; M S Gross; R S Miller; A A Waldman; S Pestka
Journal: Science Date: 1978-12-22 Impact factor: 47.728

8. Appearance of interferon inducibility and sensitivity during differentiation of murine teratocarcinoma cells in vitro.

Authors: D C Burke; C F Graham; J M Lehman
Journal: Cell Date: 1978-02 Impact factor: 41.582

9. Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography.

Authors: M W Hunkapiller; L E Hood
Journal: Biochemistry Date: 1978-05-30 Impact factor: 3.162

10. Regulation of synthesis of complement protein C4 in human fibroblasts: cell- and gene-specific effects of cytokines and lipopolysaccharide.

Authors: J Kulics; A Circolo; R C Strunk; H R Colten
Journal: Immunology Date: 1994-08 Impact factor: 7.397

10 in total

Amino-terminal amino acid sequence of human leukocyte interferon.

1. Improved manual sequencing methods.

2. Amino acid sequence studies on ten ribosomal proteins of Escherichia coli with an improved sequenator equipped with an automatic conversion device.

3. Rapid analysis of amino acid phenylthiohydantoins by high-performance liquid chromatography.

4. A device coupled to a modified sequenator for the automated conversion of anilinothiazolinones into PTH amino acids.

5. New protein sequenator with increased sensitivity.

6. Human leukocyte interferon: production, purification to homogeneity, and initial characterization.

7. Human leukocyte interferon purified to homogeneity.

8. Appearance of interferon inducibility and sensitivity during differentiation of murine teratocarcinoma cells in vitro.

9. Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography.

10. Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence.

1. NH2-terminal amino acid sequence of human fibroblast interferon.

2. Production of high levels of human leukocyte interferon from a continuous human myeloblast cell culture.

3. Construction and identification of bacterial plasmids containing nucleotide sequence for human leukocyte interferon.

4. Production of hybridomas secreting monoclonal antibodies to the human leukocyte interferons.

5. Augmentation of natural and antibody-dependent cell-mediated cytotoxicity by pure human leukocyte interferon.

6. Amino acid sequence of a human leukocyte interferon.

7. Natural human interferon-alpha 2 is O-glycosylated.

8. Evidence for a unique human fibroblast interferon (IFN-beta 1) chromosomal gene, devoid of intervening sequences.

9. Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells.

10. Regulation of synthesis of complement protein C4 in human fibroblasts: cell- and gene-specific effects of cytokines and lipopolysaccharide.