Literature DB >> 6154946

Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16.

D R Cox, L B Epstein, C J Epstein.   

Abstract

By using 12 hamster-mouse hybrids segregating a mouse T(16;17)Bnr Robertsonian translocation chromosome in conjunction with 10 similar hybrids segregating normal mouse chromosomes, we have shown that the loci that control cellular sensitivity to interferon (IfRec) and code for the soluble enzyme superoxide dismutase (SOD-1) (superoxide:superoxide oxidoreductase; EC 1.15.1.1) are syntenic in the mouse and map to mouse chromosome 16. IfRec and SOD-1 are also syntenic in man. They have previously been assigned to the distal segment of the long arm of human chromosome 21, trisomy for which causes Down syndrome. Because both IfRec and SOD-1 map to mouse chromosome 16, it will now be possible to use mice trisomic for this chromosome to determine whether certain aspects of the Down syndrome phenotype in man are caused by an altered dosage of IfRec and SOD-1.

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Year:  1980        PMID： 6154946      PMCID： PMC348673          DOI： 10.1073/pnas.77.4.2168

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  23 in total

1.  Antibodies to a cell-surface component coded by human chromosome 21 inhibit action of interferon.

Authors:  M Revel; D Bash; F H Ruddle
Journal:  Nature       Date:  1976-03-11       Impact factor: 49.962

2.  Localization fo the gene AVG for the antiviral expression of immune and classical interferon to the distal portion of the long arm of chromosome 21.

Authors:  L B Epstein; C J Epstein
Journal:  J Infect Dis       Date:  1976-06       Impact factor: 5.226

3.  Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice.

Authors:  A Gropp; H Winking; L Zech; H Müller
Journal:  Chromosoma       Date:  1972       Impact factor: 4.316

4.  Assignment of the gene for glyoxylase I to mouse chromosome 17 by somatic cell genetics.

Authors:  L Leinwand; E Nichols; F H Ruddle
Journal:  Biochem Genet       Date:  1978-08       Impact factor: 1.890

5.  Conservation of autosomal gene synteny groups in mouse and man.

Authors:  P A Lalley; J D Minna; U Francke
Journal:  Nature       Date:  1978-07-13       Impact factor: 49.962

6.  Polyethylene glycol-induced mammalian cell hybridization: effect of polyethylene glycol molecular weight and concentration.

Authors:  R L Davidson; K A O'Malley; T B Wheeler
Journal:  Somatic Cell Genet       Date:  1976-05

7.  Assignment of the gene for cytoplasmic superoxide dismutase (Sod-1) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse.

Authors:  U Francke; R T Taggart
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

8.  Partial trisomy 21. Further evidence that trisomy of band 21q22 is essential for Down's phenotype.

Authors:  A Hagemeijer; E M Smit
Journal:  Hum Genet       Date:  1977-08-31       Impact factor: 4.132

9.  Dosage effects for superoxide dismutase-1 in nucleated cells aneuploid for chromosome 21.

Authors:  W W Feaster; L W Kwok; C J Epstein
Journal:  Am J Hum Genet       Date:  1977-11       Impact factor: 11.025

10.  Assignment of a Mus musculus gene for triosephosphate isomerase to chromosome 6 and for glyoxalase-I to chromosome 17 using somatic cell hybrids.

Authors:  J D Minna; G A Bruns; A H Krinsky; P A Lalley; U Francke; P S Gerald
Journal:  Somatic Cell Genet       Date:  1978-03
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  28 in total

1.  2001 William Allan Award Address. From Down syndrome to the "human" in "human genetics".

Authors:  Charles J Epstein
Journal:  Am J Hum Genet       Date:  2001-12-26       Impact factor: 11.025

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  Somatic cell mapping of the bovine interferon-alpha receptor.

Authors:  J A Langer; R Puvanakrishnan; J E Womack
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 4.  Mouse chromosome 16.

Authors:  R H Reeves; R D Miller
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 5.  Mouse map of paralogous genes.

Authors:  J H Nadeau; M Kosowsky
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 6.  Mouse chromosome 16.

Authors:  R H Reeves; R D Miller; R Riblet
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 7.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

8.  Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.

Authors:  R H Reeves; B F O'Hara; W J Pavan; J D Gearhart; O Haller
Journal:  J Virol       Date:  1988-11       Impact factor: 5.103

9.  Human ETS2 gene on chromosome 21 is not rearranged in Alzheimer disease.

Authors:  N Sacchi; J Nalbantoglu; F R Sergovich; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

10.  Genesis and systematization of cardiovascular anomalies and analysis of skeletal malformations in murine trisomy 16 and 19. Two animal models for human trisomies.

Authors:  C Bacchus; H Sterz; W Buselmaier; S Sahai; H Winking
Journal:  Hum Genet       Date:  1987-09       Impact factor: 4.132
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