Literature DB >> 6153907

The lowest conductance state of the alamethicin pore.

W Hanke, G Boheim.   

Abstract

High resolution experiments of the alamethicin pore demonstrate the existence of a further pore state at low conductance values. This lowest resolved conductance state is found at 19 pS in 1 M KCl at room temperature. The value differs from that of the next higher conductance state by a factor of 14--15 and is approx. 20% lower than the gramicidin A pore conductance. The lowest conductance state seems to be impermeable to Ca2+, Cl-, Tris-H+ and Hepes-, whereas the higher conductance states are not.

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Year:  1980        PMID: 6153907     DOI: 10.1016/0005-2736(80)90134-0

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  45 in total

1.  An alamethicin channel in a lipid bilayer: molecular dynamics simulations.

Authors:  D P Tieleman; H J Berendsen; M S Sansom
Journal:  Biophys J       Date:  1999-04       Impact factor: 4.033

2.  Gangliosides affect membrane-channel activities dependent on ambient temperature.

Authors:  T Kappel; R H Anken; W Hanke; H Rahmann
Journal:  Cell Mol Neurobiol       Date:  2000-10       Impact factor: 5.046

3.  Ion channels of alamethicin dimer N-terminally linked by disulfide bond.

Authors:  Takashi Okazaki; Machiko Sakoh; Yasuo Nagaoka; Koji Asami
Journal:  Biophys J       Date:  2003-07       Impact factor: 4.033

Review 4.  Helical kink and channel behaviour: a comparative study with the peptaibols alamethicin, trichotoxin and antiamoebin.

Authors:  H Duclohier
Journal:  Eur Biophys J       Date:  2004-03-11       Impact factor: 1.733

5.  Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers.

Authors:  Philip A Gurnev; Ron Ortenberg; Tobias Dörr; Kim Lewis; Sergey M Bezrukov
Journal:  FEBS Lett       Date:  2012-06-21       Impact factor: 4.124

6.  Multiscale modeling of droplet interface bilayer membrane networks.

Authors:  Eric C Freeman; Amir B Farimani; Narayana R Aluru; Michael K Philen
Journal:  Biomicrofluidics       Date:  2015-11-09       Impact factor: 2.800

7.  Anion channel forming activity from the plant pathogenic bacterium Clavibacter michiganense ssp. nebraskense.

Authors:  T Schürholz; M Wilimzig; E Katsiou; R Eichenlaub
Journal:  J Membr Biol       Date:  1991-07       Impact factor: 1.843

8.  Ion channels formed by amphipathic helical peptides. A molecular modelling study.

Authors:  M S Sansom; I D Kerr; I R Mellor
Journal:  Eur Biophys J       Date:  1991       Impact factor: 1.733

9.  Bilayer lipid composition modulates the activity of dermaseptins, polycationic antimicrobial peptides.

Authors:  Hervé Duclohier
Journal:  Eur Biophys J       Date:  2006-02-14       Impact factor: 1.733

10.  Alamethicin and related peptaibols--model ion channels.

Authors:  M S Sansom
Journal:  Eur Biophys J       Date:  1993       Impact factor: 1.733

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