| Literature DB >> 6153907 |
Abstract
High resolution experiments of the alamethicin pore demonstrate the existence of a further pore state at low conductance values. This lowest resolved conductance state is found at 19 pS in 1 M KCl at room temperature. The value differs from that of the next higher conductance state by a factor of 14--15 and is approx. 20% lower than the gramicidin A pore conductance. The lowest conductance state seems to be impermeable to Ca2+, Cl-, Tris-H+ and Hepes-, whereas the higher conductance states are not.Entities:
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Year: 1980 PMID: 6153907 DOI: 10.1016/0005-2736(80)90134-0
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002