Literature DB >> 6135480

Influence of dopamine receptor agonists on gastric acid secretion induced by intraventricular administration of thyrotropin-releasing hormone in the perfused stomach of anaesthetized rats.

M Maeda-Hagiwara, K Watanabe.   

Abstract

1 The influence of dopamine receptor agonists on gastric acid secretion stimulated by thyrotropin-releasing hormone (TRH) was studied in the perfused stomach of anaesthetized rats. 2 Intraventricular TRH produced a dose-dependent stimulation of basal gastric acid secretion. 3 Pretreatment with apomorphine, bromocriptine or methamphetamine inhibited the TRH-stimulated gastric acid secretion; these drugs did not influence bethanechol-induced acid secretion. 4 Haloperidol and metoclopramide prevented the antisecretory effects of apomorphine, bromocriptine and methamphetamine. 5 The present study suggests that central dopamine receptor stimulation inhibits intraventricular TRH-induced gastric acid secretion in rats.

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Year:  1983        PMID： 6135480      PMCID： PMC2044826          DOI： 10.1111/j.1476-5381.1983.tb10524.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  24 in total

1.  The effect of clonidine on gastric acid secretion in rats and dogs.

Authors:  H M Jennewein
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000

2.  Gastric secretory changes after anterior hypothalamic lesions.

Authors:  R A Davis; F P Brooks; D C Steckel
Journal:  Am J Physiol       Date:  1968-09

3.  Electrical stimulation of hypothalamus and gastric secretion in the albino rat.

Authors:  A Misher; F P Brooks
Journal:  Am J Physiol       Date:  1966-08

4.  Central noradrenergic inhibition of gastric mucosal blood flow and acid secretion in rats.

Authors:  Y Osumi; S Aibara; K Sakae; M Fujiwara
Journal:  Life Sci       Date:  1977-04-15       Impact factor: 5.037

5.  Inhibition of gastric acid secretion and mucosal blood flow induced by intraventricularly applied neurotensin in rats.

Authors:  Y Osumi; Y Nagasaka; L H Fu; M Fujiwara
Journal:  Life Sci       Date:  1978-12-04       Impact factor: 5.037

6.  Dibenamine blockade on gastric acid secretion in vitro and its protection by histamine antagonists.

Authors:  K Watanabe; Y Goto
Journal:  Eur J Pharmacol       Date:  1975-02       Impact factor: 4.432

7.  [Pharmacological effects of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride, a new, antihypertensive substance].

Authors:  W Hoefke; W Kobinger
Journal:  Arzneimittelforschung       Date:  1966-08

8.  A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain.

Authors:  E P Noble; R J Wurtman; J Axelrod
Journal:  Life Sci       Date:  1967-02-01       Impact factor: 5.037

9.  Dopamine is a physiological regulator of thyrotrophin (TSH) secretion in normal man.

Authors:  M F Scanlon; D R Weightman; D J Shale; B Mora; M Heath; M H Snow; M Lewis; R Hall
Journal:  Clin Endocrinol (Oxf)       Date:  1979-01       Impact factor: 3.478

10.  Thyrotropin-releasing hormone in specific nuclei of rat brain.

Authors:  M J Brownstein; M Palkovits; J M Saavedra; R M Bassiri; R D Utiger
Journal:  Science       Date:  1974-07-19       Impact factor: 47.728
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  4 in total

1.  Dopamine agonists prevent duodenal ulcer relapse. A comparative study with famotidine and cimetidine.

Authors:  P Sikiric; I Rotkvic; S Mise; M Petek; R Rucman; S Seiwerth; V Zjacic-Rotkvic; M Duvnjak; V Jagic; E Suchanek
Journal:  Dig Dis Sci       Date:  1991-07       Impact factor: 3.199

Review 2.  The amygdala. Emotions and gut functions.

Authors:  P G Henke; A Ray; R M Sullivan
Journal:  Dig Dis Sci       Date:  1991-11       Impact factor: 3.199

3.  Enhancement by intracerebroventricular thyrotropin-releasing hormone of indomethacin-induced gastric lesions in the rat.

Authors:  M Maeda-Hagiwara; H Watanabe; K Watanabe
Journal:  Br J Pharmacol       Date:  1983-12       Impact factor: 8.739

4.  Intracerebroventricular injection of a TRH analogue, gamma-butyrolactone-gamma-carbonyl-L-histidyl-prolinamide, induces gastric lesions and gastric acid stimulation in rats.

Authors:  M Maeda-Hagiwara; H Watanabe
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-08       Impact factor: 3.000
  4 in total

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