Literature DB >> 6130380

Production of human monoclonal antibody to rhesus D antigen.

D H Crawford, M J Barlow, J F Harrison, L Winger, E R Huehns.   

Abstract

Peripheral-blood mononuclear cells from an individual known to produce antibody to the rhesus D blood group were enriched for specific antibody-producing cells before transformation with Epstein-Barr virus. An anti-rhesus-D antibody-producing cell line (UCH D4) was obtained and cloned. Culture supernatants contained about 20 micrograms/ml of rhesus-D-specific IgG-class antibody. The antibody reactivity compared well with that of reagents used routinely for rhesus blood-grouping.

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Year:  1983        PMID： 6130380     DOI： 10.1016/s0140-6736(83)91502-7

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  12 in total

1.  Human monoclonal antibodies to C, c, E, e and G antigens of the Rh system.

Authors:  K Thompson; G Barden; J Sutherland; I Beldon; M Melamed
Journal:  Immunology       Date:  1990-11       Impact factor: 7.397

2.  Expression of a human monoclonal anti-(rhesus D) Fab fragment in Escherichia coli with the use of bacteriophage lambda vectors.

Authors:  R A Williamson; M A Persson; D R Burton
Journal:  Biochem J       Date:  1991-07-15       Impact factor: 3.857

3.  Monoclonal antibodies.

Authors:  S P Cole
Journal:  Can Fam Physician       Date:  1987-02       Impact factor: 3.275

4.  Rh(D) haemolytic disease of the newborn: the changing scene.

Authors:  S J Urbaniak
Journal:  Br Med J (Clin Res Ed)       Date:  1985-07-06

5.  Requirements for growth of Epstein-Barr virus-transformed cells at low cell densities.

Authors:  R F Tiebout; R W Sauerwein; W G van der Meer; F van Boxtel-Oosterhof; W P Zeijlemaker
Journal:  Immunology       Date:  1987-02       Impact factor: 7.397

Review 6.  Monoclonal antibodies in clinical medicine.

Authors:  H M Dick
Journal:  Br Med J (Clin Res Ed)       Date:  1985-09-21

7.  Generating human monoclonal antibodies.

Authors:  A M Neville; P A Edwards; M J O'Hare
Journal:  Med Oncol Tumor Pharmacother       Date:  1984

8.  Monoclonal antibodies in diagnosis and treatment.

Authors:  G Morgan; R J Levinsky
Journal:  Arch Dis Child       Date:  1985-02       Impact factor: 3.791

9.  Efficient generation in vitro, from human peripheral blood cells, of monoclonal Epstein-Barr virus transformants producing specific antibody to a variety of antigens without prior deliberate immunization.

Authors:  L Winger; C Winger; P Shastry; A Russell; M Longenecker
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

Review 10.  Human monoclonal antibodies.

Authors:  S P Cole; B G Campling; T Atlaw; D Kozbor; J C Roder
Journal:  Mol Cell Biochem       Date:  1984-06       Impact factor: 3.396
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