Literature DB >> 2269469

Human monoclonal antibodies to C, c, E, e and G antigens of the Rh system.

K Thompson1, G Barden, J Sutherland, I Beldon, M Melamed.   

Abstract

A panel of heterohybridomas secreting human IgG and IgM monoclonal antibodies to the C, c, G, E, and e antigens of the Rh system has been established. Both classes of antibody have been shown to react with red blood cells carrying their respective antigens; those of the IgM class being able to directly agglutinate unmodified red blood cells in saline. The heterohybridomas have been shown to be suitable for bulk culture and produce levels of antibody in the range of 15-73 micrograms/ml in the spent culture supernatant.

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Year:  1990        PMID： 2269469      PMCID： PMC1384426     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  16 in total

1.  Differences between the activities of human monoclonal IgG1 and IgG3 subclasses of anti-D(Rh) antibody in their ability to mediate red cell-binding to macrophages.

Authors:  E Wiener; A Atwal; K M Thompson; M D Melamed; B Gorick; N C Hughes-Jones
Journal:  Immunology       Date:  1987-11       Impact factor: 7.397

2.  Requirements for the establishment of heterohybridomas secreting monoclonal human antibody to rhesus (D) blood group antigen.

Authors:  M D Melamed; K M Thompson; T Gibson; N C Hughes-Jones
Journal:  J Immunol Methods       Date:  1987-11-23       Impact factor: 2.303

3.  Heterogeneity of EBV-transformable human B lymphocyte populations.

Authors:  M A Chan; L D Stein; H M Dosch; N H Sigal
Journal:  J Immunol       Date:  1986-01       Impact factor: 5.422

4.  Production of human monoclonal IgG and IgM antibodies with anti-D (rhesus) specificity using heterohybridomas.

Authors:  K M Thompson; M D Melamed; K Eagle; B D Gorick; T Gibson; A M Holburn; N C Hughes-Jones
Journal:  Immunology       Date:  1986-05       Impact factor: 7.397

5.  Immunogenic and antigenic epitopes of immunoglobulins binding of human monoclonal anti-D antibodies to FcRI on the monocyte-like U937 cell line.

Authors:  M R Walker; B M Kumpel; K Thompson; J M Woof; D R Burton; R Jefferis
Journal:  Vox Sang       Date:  1988       Impact factor: 2.144

6.  Production of human monoclonal antibody to rhesus D antigen.

Authors:  D H Crawford; M J Barlow; J F Harrison; L Winger; E R Huehns
Journal:  Lancet       Date:  1983-02-19       Impact factor: 79.321

7.  Differences between the activities of human monoclonal IgG1 and IgG3 anti-D antibodies of the Rh blood group system in their abilities to mediate effector functions of monocytes.

Authors:  E Wiener; V M Jolliffe; H C Scott; B M Kumpel; K M Thompson; M D Melamed; N C Hughes-Jones
Journal:  Immunology       Date:  1988-10       Impact factor: 7.397

8.  Human monoclonal antibodies to Rh0(D).

Authors:  S K Foung; J A Blunt; P S Wu; P Ahearn; L C Winn; E G Engleman; F C Grumet
Journal:  Vox Sang       Date:  1987       Impact factor: 2.144

9.  Human monoclonal antibodies against blood group antigens. Preparation of a series of stable EBV immortalized B clones producing high levels of antibody of different isotypes and specificities.

Authors:  D Goossens; F Champomier; P Rouger; C Salmon
Journal:  J Immunol Methods       Date:  1987-08-03       Impact factor: 2.303

10.  Human monoclonal anti-D antibodies. II. The relationship between IgG subclass, Gm allotype and Fc mediated function.

Authors:  B M Kumpel; E Wiener; S J Urbaniak; B A Bradley
Journal:  Br J Haematol       Date:  1989-03       Impact factor: 6.998
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  6 in total

1.  Human monoclonal antibodies specific for blood group antigens demonstrate multispecific properties characteristic of natural autoantibodies.

Authors:  K M Thompson; J Sutherland; G Barden; M D Melamed; M G Wright; S Bailey; S J Thorpe
Journal:  Immunology       Date:  1992-05       Impact factor: 7.397

2.  Control of autoantibody affinity by selection against amino acid replacements in the complementarity-determining regions.

Authors:  M Børretzen; I Randen; E Zdárský; O Førre; J B Natvig; K M Thompson
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

3.  Human monoclonal antibodies specific to hepatitis B virus generated in a human/mouse radiation chimera: the Trimera system.

Authors:  R Eren; I Lubin; D Terkieltaub; O Ben-Moshe; A Zauberman; R Uhlmann; T Tzahor; S Moss; E Ilan; D Shouval; E Galun; N Daudi; H Marcus; Y Reisner; S Dagan
Journal:  Immunology       Date:  1998-02       Impact factor: 7.397

4.  Human monoclonal rheumatoid factors: incidence of cross-reactions with tissue components and correlation with VH gene usage.

Authors:  S J Thorpe; M Børretzen; S W Bailey; I Randen; J B Natvig; K M Thompson
Journal:  Immunology       Date:  1994-09       Impact factor: 7.397

5.  Generation of antibody-producing hybridomas following one single immunization with a targeted DNA vaccine.

Authors:  I Øynebråten; T-O Løvås; K Thompson; B Bogen
Journal:  Scand J Immunol       Date:  2012-04       Impact factor: 3.487

6.  Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin.

Authors:  Gunnveig Grødeland; Marta Baranowska-Hustad; Justin Abadejos; Tanya R Blane; John Teijaro; David Nemazee; Bjarne Bogen
Journal:  Front Immunol       Date:  2020-03-25       Impact factor: 7.561
  6 in total

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