Literature DB >> 6129679

Recent progress in the medicinal chemistry of 2,4-diaminopyrimidines.

B Roth, C C Cheng.   

Abstract

Entities:  

Mesh:

Substances:

Year:  1982        PMID: 6129679     DOI: 10.1016/s0079-6468(08)70332-1

Source DB:  PubMed          Journal:  Prog Med Chem        ISSN: 0079-6468


× No keyword cloud information.
  9 in total

Review 1.  Synthesis, reactivity, and biological activity of 5-aminouracil and its derivatives.

Authors:  Raafat Mohamed Shaker; Mohamed Abd Elrady; Kamal Usef Sadek
Journal:  Mol Divers       Date:  2015-04-30       Impact factor: 2.943

2.  Fragment-based discovery of novel thymidylate synthase leads by NMR screening and group epitope mapping.

Authors:  Darren W Begley; Suxin Zheng; Gabriele Varani
Journal:  Chem Biol Drug Des       Date:  2010-07-05       Impact factor: 2.817

3.  A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductase.

Authors:  U C Singh; S J Benkovic
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

Review 4.  5-Methyltetrahydrohomofolate.

Authors:  P J O'Dwyer; B H Wagner; D F Hoth; B Leyland-Jones
Journal:  Invest New Drugs       Date:  1987       Impact factor: 3.850

5.  A 1H n.m.r. study of the role of the glutamate moiety in the binding of methotrexate to Lactobacillus casei dihydrofolate reductase.

Authors:  D J Antonjuk; B Birdsall; H T Cheung; G M Clore; J Feeney; A Gronenborn; G C Roberts; T Q Tran
Journal:  Br J Pharmacol       Date:  1984-02       Impact factor: 8.739

Review 6.  Biological and biochemical properties of new anticancer folate antagonists.

Authors:  D W Fry; R C Jackson
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

7.  Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region.

Authors:  Robin A Fairhurst; Thomas Knoepfel; Catherine Leblanc; Nicole Buschmann; Christoph Gaul; Jutta Blank; Inga Galuba; Jörg Trappe; Chao Zou; Johannes Voshol; Christine Genick; Peggy Brunet-Lefeuvre; Francis Bitsch; Diana Graus-Porta; Pascal Furet
Journal:  Medchemcomm       Date:  2017-06-08       Impact factor: 3.597

Review 8.  Significance and biological importance of pyrimidine in the microbial world.

Authors:  Vinita Sharma; Nitin Chitranshi; Ajay Kumar Agarwal
Journal:  Int J Med Chem       Date:  2014-03-23

Review 9.  Trimethoprim and other nonclassical antifolates an excellent template for searching modifications of dihydrofolate reductase enzyme inhibitors.

Authors:  Agnieszka Wróbel; Karolina Arciszewska; Dawid Maliszewski; Danuta Drozdowska
Journal:  J Antibiot (Tokyo)       Date:  2019-10-02       Impact factor: 2.649

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.