Literature DB >> 6117607

beta-Alanine, a possible neurotransmitter in the visual system?

M Sandberg, I Jacobson.   

Abstract

The chemically evoked efflux of endogenous amino acids from perfused rabbit superior colliculus (SC) slices was studied. Amino acids in the perfusates were determined fluorimetrically with a precolumn derivatisation method and subsequent separation on an HPLC column. Potassium-induced depolarisation caused a calcium-dependent release of beta-alanine, GABA, glutamate, and aspartate. Veratridine-evoked efflux was essentially similar in selectivity and could be blocked by tetrodotoxin (TTX). The results are indicative of a neurotransmitter role of beta-alanine, GABA, glutamate, and aspartate in the SC of the rabbit.

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Year:  1981        PMID： 6117607     DOI： 10.1111/j.1471-4159.1981.tb04691.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  13 in total

1.  Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties.

Authors:  Zoran Gojkovic; Lise Rislund; Birgit Andersen; Michael P B Sandrini; Paul F Cook; Klaus D Schnackerz; Jure Piskur
Journal:  Nucleic Acids Res       Date:  2003-03-15       Impact factor: 16.971

2.  Crystallization and X-ray diffraction analysis of dihydropyrimidinase from Saccharomyces kluyveri.

Authors:  Doreen Dobritzsch; Birgit Andersen; Jure Piskur
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-03-12

3.  Purification, crystallization and X-ray diffraction analysis of dihydropyrimidinase from Dictyostelium discoideum.

Authors:  Bernhard Lohkamp; Birgit Andersen; Jure Piskur; Doreen Dobritzsch
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-12-16

4.  Amino acid profiles in Long-Evans rat superior colliculus, visual cortex, and inferior colliculus.

Authors:  G T Golden; T N Ferraro; R G Fariello; T A Hare
Journal:  Neurochem Res       Date:  1989-05       Impact factor: 3.996

Review 5.  Amino acid neurotransmission: dynamics of vesicular uptake.

Authors:  E M Fykse; F Fonnum
Journal:  Neurochem Res       Date:  1996-09       Impact factor: 3.996

6.  Effect of taurine supplementation on hepatic metabolism and alleviation of cadmium toxicity and bioaccumulation in a marine teleost, red sea bream, Pagrus major.

Authors:  Takeshi Hano; Katsutoshi Ito; Kumiko Kono; Mana Ito; Nobuyuki Ohkubo; Kazuhiko Mochida
Journal:  Fish Physiol Biochem       Date:  2016-08-17       Impact factor: 2.794

7.  Eukaryotic beta-alanine synthases are functionally related but have a high degree of structural diversity.

Authors:  Z Gojković; M P Sandrini; J Piskur
Journal:  Genetics       Date:  2001-07       Impact factor: 4.562

8.  Dihydropyrimidine dehydrogenase deficiency and acute neurological presentation.

Authors:  A Fiumara; A B P van Kuilenburg; U Caruso; C Nucifora; E Marzullo; R Barone; C Meli; A H van Gennip
Journal:  J Inherit Metab Dis       Date:  2003       Impact factor: 4.982

9.  beta-Alanine transport into plasma membrane vesicles derived from rat brain synaptosomes.

Authors:  F Zafra; M C Aragon; F Valdivieso; C Gimenez
Journal:  Neurochem Res       Date:  1984-05       Impact factor: 3.996

10.  A re-examination of the Na+-independent binding of [3H]beta-alanine to rat brain stem-spinal cord.

Authors:  L M Orensanz; E Ambrosio; I Fernández; M T Montero
Journal:  Neurochem Res       Date:  1988-12       Impact factor: 3.996
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