Literature DB >> 6090900

Presence of a bent helix in fragments of kinetoplast DNA minicircles from several trypanosomatid species.

J M Ntambi, J C Marini, J D Bangs, S L Hajduk, H E Jimenez, P A Kitchin, V A Klein, K A Ryan, P T Englund.   

Abstract

Some restriction fragments of kinetoplast minicircles from several trypanosomatid species (Leishmania tarentolae, Trypanosoma brucei, T. equiperdum, Herpetomonas muscarum, Crithidia fasciculata, but not T. cruzi) migrate anomalously on polyacrylamide gels. This behavior is probably due to a natural curvature of the helix. Bent helices appear to be a common property of kinetoplast minicircles, and may be important for minicircle function. In the case of T. equiperdum, we present evidence that each minicircle has a single bent region which resides in or near the 'conserved sequence.'

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Year:  1984        PMID： 6090900     DOI： 10.1016/0166-6851(84)90084-7

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  15 in total

1.  Trypanosoma equiperdum minicircles encode three distinct primary transcripts which exhibit guide RNA characteristics.

Authors:  V W Pollard; S L Hajduk
Journal:  Mol Cell Biol       Date:  1991-03       Impact factor: 4.272

2.  Leishmania tarentolae minicircles of different sequence classes encode single guide RNAs located in the variable region approximately 150 bp from the conserved region.

Authors:  N R Sturm; L Simpson
Journal:  Nucleic Acids Res       Date:  1991-11-25       Impact factor: 16.971

3.  A knotted free minicircle in kinetoplast DNA.

Authors:  K A Ryan; T A Shapiro; C A Rauch; J D Griffith; P T Englund
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

4.  Sequence-directed bent DNA helix is the specific binding site for Crithidia fasciculata nicking enzyme.

Authors:  M Linial; J Shlomai
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  Replication of DNA minicircles in kinetoplasts isolated from Crithidia fasciculata: structure of nascent minicircles.

Authors:  C Sheline; T Melendy; D S Ray
Journal:  Mol Cell Biol       Date:  1989-01       Impact factor: 4.272

6.  kDNA minicircles of the major sequence class of C. fasciculata contain a single region of bent helix widely separated from the two origins of replication.

Authors:  D S Ray; J C Hines; H Sugisaki; C Sheline
Journal:  Nucleic Acids Res       Date:  1986-10-24       Impact factor: 16.971

7.  Mitochondrial minicircles in the free-living bodonid Bodo saltans contain two gRNA gene cassettes and are not found in large networks.

Authors:  D Blom; A de Haan; J van den Burg; M van den Berg; P Sloof; M Jirku; J Lukes; R Benne
Journal:  RNA       Date:  2000-01       Impact factor: 4.942

8.  Conserved repeats in the kinetoplast maxicircle divergent region of Leishmania sp. and Leptomonas seymouri.

Authors:  Pavel N Flegontov; Qiang Guo; Lina Ren; Margarita V Strelkova; Alexander A Kolesnikov
Journal:  Mol Genet Genomics       Date:  2006-08-15       Impact factor: 3.291

Review 9.  Molecular parasitology in the 21st century.

Authors:  Roberto Docampo
Journal:  Essays Biochem       Date:  2011       Impact factor: 8.000

10.  Isolation of proteins associated with kinetoplast DNA networks in vivo.

Authors:  C Xu; D S Ray
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205
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