| Literature DB >> 6090850 |
G Oppenheim, J Mintzer, Y Halperin, R Eliakim, J Stessman, R P Ebstein.
Abstract
The effect of prior incubation with a single concentration of isoproterenol (10(-4) M) for 2 hours at 37 degrees C on isoproterenol-stimulated cyclic AMP accumulation in intact lymphocytes from young, old and subjects with Alzheimer's disease was studied. In lymphocytes from all three subjects groups prior incubation of cells with isoproterenol resulted in a significant reduction of cyclic AMP accumulation upon subsequent stimulation with isoproterenol.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6090850 DOI： 10.1016/0024-3205(84)90277-7
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037