Literature DB >> 3015668

Hormone and forskolin-stimulated cyclic AMP accumulation in human lymphocytes: reliability of longitudinal time measurements.

R P Ebstein, J Mintzer, Y Lipschitz, Z Shemesh, J Stessman.   

Abstract

Reliability of measurement of lymphocyte cyclic AMP synthesis in intact cells was estimated by taking 3 successive blood samples during a one-month period from 11 healthy volunteers. Isoproterenol and prostaglandin E1-stimulated cyclic AMP accumulation were used to evaluate the activity of these two receptor activities in human lymphocytes. Forskolin-stimulated cyclic AMP accumulation was used to evaluate the activity of the Ns/catalytic subunit. Only for forskolin was significant reliability observed. For isoproterenol and prostaglandin E1 significant reliability was observed only for male subjects.

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Year:  1986        PMID： 3015668     DOI： 10.1007/bf01941546

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  25 in total

1.  Beta-adrenergic receptor function in affective illness.

Authors:  G N Pandey; M W Dysken; D L Garver; J M Davis
Journal:  Am J Psychiatry       Date:  1979-05       Impact factor: 18.112

2.  Properties of cyclic 3',5'-nucleotide phosphodiesterase from rat brain.

Authors:  W Y Cheung
Journal:  Biochemistry       Date:  1967-04       Impact factor: 3.162

3.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

4.  Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly.

Authors:  R D Feldman; L E Limbird; J Nadeau; D Robertson; A J Wood
Journal:  N Engl J Med       Date:  1984-03-29       Impact factor: 91.245

5.  High affinity beta-2-adrenergic receptors in mononuclear leucocytes: similar density in young and old normal subjects.

Authors:  R Landmann; H Bittiger; F R Bühler
Journal:  Life Sci       Date:  1981-10-26       Impact factor: 5.037

6.  Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.

Authors:  R A Cerione; B Strulovici; J L Benovic; C D Strader; M G Caron; R J Lefkowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

7.  Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes.

Authors:  I B Abrass; P J Scarpace
Journal:  J Clin Endocrinol Metab       Date:  1982-11       Impact factor: 5.958

8.  Interaction of forskolin with dually regulated adenylate cyclase.

Authors:  K B Seamon; B Wetzel
Journal:  Adv Cyclic Nucleotide Protein Phosphorylation Res       Date:  1984

9.  Alzheimer's disease: isoproterenol and prostaglandin E1-stimulated cyclic AMP accumulation in lymphocytes.

Authors:  R P Ebstein; G Oppenheim; J Stessman
Journal:  Life Sci       Date:  1984-06-04       Impact factor: 5.037

10.  Changes in the density of beta adrenergic receptors in rat lymphocytes, heart and lung after chronic treatment with propranolol.

Authors:  R D Aarons; P B Molinoff
Journal:  J Pharmacol Exp Ther       Date:  1982-05       Impact factor: 4.030
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