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Literature DB >> 6083551

Divergence of U2 snRNA sequences in the genome of D. melanogaster.

A Alonso, E Beck, J L Jorcano, B Hovemann.

Abstract

Four different U2-snRNA genes/related sequences of D. melanogaster were cloned and characterized. The sequences of all four genes suggest that they were generated by a DNA-mediated mechanism. These genes/related sequences were found to be located in two loci, each locus containing two U2 snRNA sequences. Using coding sequences as well as flanking sequences as hybridization probes against polytene chromosomes of D. melanogaster Oregon R we were able to map these loci separately at positions 34BC and 84C. By Northern analysis we observed that the quantities of U2- and U1-snRNA are coordinated and change during the embryonic development of the fly.

Entities: Gene Species

Mesh：

Substances：
RNA, Small Nuclear
RNA

Year: 1984 PMID： 6083551 PMCID： PMC320479 DOI： 10.1093/nar/12.24.9543

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

17 in total

1. Either gene amplification or gene conversion may maintain the homogeneity of the multigene family encoding human U1 small nuclear RNA.

Authors: A M Weiner; R A Denison
Journal: Cold Spring Harb Symp Quant Biol Date: 1983

4. Analysis of a sea urchin gene cluster coding for the small nuclear U7 RNA, a rare RNA species implicated in the 3' editing of histone precursor mRNAs.

Authors: M De Lorenzi; U Rohrer; M L Birnstiel
Journal: Proc Natl Acad Sci U S A Date: 1986-05 Impact factor: 11.205

Divergence of U2 snRNA sequences in the genome of D. melanogaster.

1. Either gene amplification or gene conversion may maintain the homogeneity of the multigene family encoding human U1 small nuclear RNA.

2. Genes and pseudogenes for mouse U1 and U2 small nuclear RNAs.

3. Isolation and characterization of two linked mouse U1b small nuclear RNA genes.

4. SnRNAs, SnRNPs, and RNA processing.

5. Cross-reaction of snRNA and an Alu I-like sequence from rat with DNAs from different eucaryotic species.

6. Are snRNPs involved in splicing?

7. Human U1 RNA pseudogenes may be generated by both DNA- and RNA-mediated mechanisms.

8. The genes coding for 4 snRNAs of Drosophila melanogaster: localization and determination of gene numbers.

9. Isolation and characterization of Drosophila melanogaster U2 small nuclear RNA genes.

10. Sea urchin small nuclear RNA genes are organized in distinct tandemly repeating units.

1. Analysis of spliceosome assembly and the structure of a regulated intron in Drosophila in vitro splicing extracts.

2. Compilation of small RNA sequences.

3. Compilation of small RNA sequences.

4. Analysis of a sea urchin gene cluster coding for the small nuclear U7 RNA, a rare RNA species implicated in the 3' editing of histone precursor mRNAs.

5. Drosophila melanogaster genes for U1 snRNA variants and their expression during development.

6. Structure of U2 snRNA genes of Arabidopsis thaliana and their expression in electroporated plant protoplasts.

7. Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region.

Review 8. Pre-messenger RNA processing factors in the Drosophila genome.