Literature DB >> 6195341

Isolation and characterization of Drosophila melanogaster U2 small nuclear RNA genes.

A Alonso, J L Jorcano, E Beck, E Spiess.   

Abstract

We describe here the organization of DNA sequences complementary to Drosophila melanogaster U2 small nuclear (sn) RNA. From a genomic library we isolated two recombinants containing two genes each. Genomic reconstruction experiments and Southern analysis revealed that D. melanogaster possesses only four to five U2 snRNA genes or very closely related sequences. The nucleotide sequence of one of the clones analysed shows 77% homology with rat U2 snRNA. A stretch of 12 nucleotides that has been implicated in heterogeneous nuclear RNA splicing is conserved between rat and Drosophila. The genomic organization of these genes is very similar in different melanogaster strains but diverges highly in different Drosophila species.

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Year:  1983        PMID： 6195341     DOI： 10.1016/s0022-2836(83)80165-x

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


  12 in total

1.  Intron splicing: a conserved internal signal in introns of Drosophila pre-mRNAs.

Authors:  E B Keller; W A Noon
Journal:  Nucleic Acids Res       Date:  1985-07-11       Impact factor: 16.971

2.  Compilation of small RNA sequences.

Authors:  R Reddy
Journal:  Nucleic Acids Res       Date:  1986       Impact factor: 16.971

3.  Compilation of small RNA sequences.

Authors:  R Reddy
Journal:  Nucleic Acids Res       Date:  1985       Impact factor: 16.971

4.  Compilation of small RNA sequences.

Authors:  R Reddy
Journal:  Nucleic Acids Res       Date:  1988       Impact factor: 16.971

5.  Nucleotide sequence of a bean (Phaseolus vulgaris) U1 small nuclear RNA gene: implications for plant pre-mRNA splicing.

Authors:  V L van Santen; R A Spritz
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

6.  The U2 RNA analogue of Trypanosoma brucei gambiense: implications for a splicing mechanism in trypanosomes.

Authors:  C Tschudi; F F Richards; E Ullu
Journal:  Nucleic Acids Res       Date:  1986-11-25       Impact factor: 16.971

7.  Divergence of U2 snRNA sequences in the genome of D. melanogaster.

Authors:  A Alonso; E Beck; J L Jorcano; B Hovemann
Journal:  Nucleic Acids Res       Date:  1984-12-21       Impact factor: 16.971

8.  Clustered genes for human U2 RNA.

Authors:  G Westin; J Zabielski; K Hammarström; H J Monstein; C Bark; U Pettersson
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

9.  A complete and a truncated U1 snRNA gene of Drosophila melanogaster are found as inverted repeats at region 82E of the polytene chromosomes.

Authors:  J Kejzlarová-Lepesant; H W Brock; J Moreau; M L Dubertret; A Billault; J A Lepesant
Journal:  Nucleic Acids Res       Date:  1984-12-11       Impact factor: 16.971

10.  A structural analysis of P. polycephalum U1 RNA at the RNA and gene levels. Are there differentially expressed U1 RNA genes in P. polycephalum? U1 RNA evolution.

Authors:  E Myslinski; F X Wilhelm; C Branlant
Journal:  Nucleic Acids Res       Date:  1989-02-11       Impact factor: 16.971
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