| Literature DB >> 6015694 |
Abstract
A mutant strain of the Friend leukemia virus is described. The parental virus strain, passaged through ICR/Ha mice, shows no or very little activity by the spleen-focus assay in BALB/c mice (by comparison with highly susceptible DBA/2 and ICR/Ha mice) and produces typical Friend disease in these mice only exceptionally; susceptibility to this strain of virus is recessive in the (C57BL/6 x DBA/2) F(1). By contrast, the mutant virus strain is as active in BALB/c mice as in DBA/2 or ICR/Ha mice; susceptibility to the mutant virus strain is dominant in the (C57BL/6 x DBA/2) F(1).Entities:
Mesh：
Year: 1967 PMID： 6015694 DOI： 10.1126/science.155.3761.461
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728