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Literature DB >> 599183

Application of a screening test for antibody the hepatitis B core antigen.

Abstract

Hepatitis B core antigen (HBcAg) was prepared from human liver tissue and used in an immunoelectro-osmophoresis screening test to detect antibody to HBcAg (anti-HBc) in patients with evidence of liver disease and in blood donors. With the exception of two immunosuppressed HBsAg carriers, anti-HBc was found in all cases of hepatitis B infection even when HBsAg was detectable only by radioimmunoassay. Non-specific reactions were observed in 'non-B' hepatitis but, in spite of this problem, antib-HBc screening was considered a useful addition to routine tests in the clinical hepatitis laboratory.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1977 PMID： 599183 PMCID： PMC476529 DOI： 10.1136/jcp.30.8.709

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

7 in total

1. Antibody to hepatitis-B-virus core in man.

Authors: J H Hoofnagle; R J Gerety; L F Barker
Journal: Lancet Date: 1973-10-20 Impact factor: 79.321

2. New specificities in Australia antigen positive sera distinct from the Le Bouvier determinants.

Authors: L O Magnius; J A Espmark
Journal: J Immunol Date: 1972-11 Impact factor: 5.422

3. Letter: Immunoelectro-osmophoresis for detection of antibody to hepatitis B core antigen.

Authors: A Budkowska; B Walicka; G Domaniewska; W J Brzosko
Journal: N Engl J Med Date: 1974-06-27 Impact factor: 91.245

4. Duality of hepatitis B antigen and its antibody. I. Immunofluorescence studies.

Authors: W J Brzosko; K Madaliński; K Krawczyński; A Nowoslawski
Journal: J Infect Dis Date: 1973-04 Impact factor: 5.226

5. Hepatitis B core antigen. Detection of antibody by radioimmunoprecipitation.

Authors: Y Moritsugu; J W Gold; J Wagner; R Y Dodd; R H Purcell
Journal: J Immunol Date: 1975-06 Impact factor: 5.422

6. Pitfalls in the study of hepatitis A.

Authors: J D Almeida; F W Gay; T G Wreghitt
Journal: Lancet Date: 1974-09-28 Impact factor: 79.321

7. Effects of cyclophosphamide on hepatitis B virus infection and challenge in chimpanzees.

Authors: J A Markenson; R J Gerety; J H Hoofnagle; L F Barker
Journal: J Infect Dis Date: 1975-02 Impact factor: 5.226

7 in total

10 in total

1. Passive hemagglutination test for antibody to hepatitis B core antigen.

Authors: B Petchclai; K Khupulsup; C Wasi; N Bhamarapravati
Journal: J Clin Microbiol Date: 1986-10 Impact factor: 5.948

2. Chronic persistent hepatitis: hepatitis B virus markers and histological follow-up.

Authors: R G Chadwick; J Galizzi; J Heathcote; T Lyssiotis; B J Cohen; P J Scheuer; S Sherlock
Journal: Gut Date: 1979-05 Impact factor: 23.059

3. Horizontal transmission of hepatitis B virus amongst British 2nd World War soldiers in South-East Asia.

Authors: G V Gill; D R Bell; E M Vandervelde
Journal: Postgrad Med J Date: 1991-01 Impact factor: 2.401

4. Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis.

Authors: S Stahl; P MacKay; M Magazin; S A Bruce; K Murray
Journal: Proc Natl Acad Sci U S A Date: 1982-03 Impact factor: 11.205

5. Hepatitis B core antigen synthesised in Escherichia coli: its use for antibody screening in patients attending a clinic for sexually transmitted diseases.

Authors: B J Cohen; P A Litton; P P Mortimer; P Simmons
Journal: J Hyg (Lond) Date: 1984-10