| Literature DB >> 47880 |
Y Moritsugu, J W Gold, J Wagner, R Y Dodd, R H Purcell.
Abstract
Radioactive cores were prepared from concentrated Dane particles by DNA polymerase reaction followed by CsCl density gradient centrifugation. Two radioactive peaks were obtained: one peak with an average density of 1.36 g/cm-3 in CsCl contained cores that possessed full serologic reactivity; the other peak, with a density of 1.28 to 1.32 g/cm-3, contained cores associated with globulin. A double antibody immunoprecipitation test was developed, using the radioactive heavy cores as a source of antigen. The test was at least 300 times as sensitive as complement fixation for detecting antibody to core.Entities:
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Year: 1975 PMID： 47880
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422