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Literature DB >> 597245

The effects of inhibition of fatty acid oxidation in suckling newborn rats.

Abstract

Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential to support gluconeogenesis and to maintain normal blood [glucose] in suckling newborn rats.

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Year: 1977 PMID： 597245 PMCID： PMC1165049 DOI： 10.1042/bj1660631

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

18 in total

1. The physical and chemical characterization of rat's milk.

Authors: T D LUCKEY; T J MENDE; J PLEASANTS
Journal: J Nutr Date: 1954-11-10 Impact factor: 4.798

2. Evidence that fatty acid oxidation stimulates gluconeogenesis in newborn rats [proceedings].

Authors: P R Ferré; J P Pegorier; J R Girard; E B Marliss
Journal: Biochem Soc Trans Date: 1977 Impact factor: 5.407

3. Control factors affecting gluconeogenesis in perfused rat liver. Effects of 4-pentenoic acid.

Authors: J R Williamson; S G Rostand; M J Peterson
Journal: J Biol Chem Date: 1970-06 Impact factor: 5.157

4. Gluconeogenesis in the newborn rat: the substrates and their quantitative significance.

Authors: K Snell; D G Walker
Journal: Enzyme Date: 1973

5. Alanine and gluconeogenesis in man: effect of ethanol.

Authors: R A Kreisberg; A M Siegal; W C Owen
Journal: J Clin Endocrinol Metab Date: 1972-05 Impact factor: 5.958

6. Inhibition of hepatic gluconeogenesis and fatty acid oxidation by pent-4-enoic acid.

Authors: N B Ruderman; C J Toews; C Lowy; I Vreeland; E Shafrir
Journal: Am J Physiol Date: 1970-07

7. The effects of inhibition of gluconeogenesis in suckling newborn rats.

Authors: P Ferre; J P Pegorier; J Girard
Journal: Biochem J Date: 1977-01-15 Impact factor: 3.857

8. Fuels, hormones, and liver metabolism at term and during the early postnatal period in the rat.

Authors: J R Girard; G S Cuendet; E B Marliss; A Kervran; M Rieutort; R Assan
Journal: J Clin Invest Date: 1973-12 Impact factor: 14.808

9. Effects of exogenous hormones and glucose on plasma levels and hepatic metabolism of amino acids in the fetus and in the newborn rat.

Authors: J R Girard; I Guillet; J Marty; R Assan; E B Marliss
Journal: Diabetologia Date: 1976-08 Impact factor: 10.122

10. Hormonal control of [14C]glucose synthesis from [U-14C]dihydroxyacetone and glycerol in isolated rat hepatocytes.

Authors: S J Pilkis; J P Riou; T H Claus
Journal: J Biol Chem Date: 1976-12-25 Impact factor: 5.157

6 in total

1. Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats.

Authors: P Ferré; P Satabin; L El Manoubi; S Callikan; J Girard
Journal: Biochem J Date: 1981-11-15 Impact factor: 3.857

2. Evidence for the participation of aspartate aminotransferase in hepatic glucose synthesis in the suckling newborn rat.

Authors: P Ferré; D H Williamson
Journal: Biochem J Date: 1978-10-15 Impact factor: 3.857

3. The early development of white adipose tissue. Effects of litter size on the lipoprotein lipase activity of four adipose-tissue depots, serum immunoreactive insulin and tissue cellularity during the first four weeks of life in the rat.

Authors: A Cryer; H M Jones
Journal: Biochem J Date: 1979-03-15 Impact factor: 3.857