Literature DB >> 849278

The effects of inhibition of gluconeogenesis in suckling newborn rats.

P Ferre, J P Pegorier, J Girard.   

Abstract

Inhibition of gluconeogenesis with 3-mercaptopicolinate in suckling newborn rats caused a fall in blood [glucose], but no change in their high plasma [free fatty acid] and blood [ketone bodies]. Active gluconeogenesis seems to be more important than sparing of glucose by high concentrations of fat-derived substrates for the maintenance of normal blood [glucose] in suckling newborn rats.

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Year:  1977        PMID： 849278      PMCID： PMC1164587          DOI： 10.1042/bj1620209

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  19 in total

1.  The physical and chemical characterization of rat's milk.

Authors:  T D LUCKEY; T J MENDE; J PLEASANTS
Journal:  J Nutr       Date:  1954-11-10       Impact factor: 4.798

2.  Changes in activity of some enzymes involved in glucose utilization and formation in developing rat liver.

Authors:  R G Vernon; D G Walker
Journal:  Biochem J       Date:  1968-01       Impact factor: 3.857

3.  Gluconeogenesis in the newborn rat: the substrates and their quantitative significance.

Authors:  K Snell; D G Walker
Journal:  Enzyme       Date:  1973

4.  Alanine and gluconeogenesis in man: effect of ethanol.

Authors:  R A Kreisberg; A M Siegal; W C Owen
Journal:  J Clin Endocrinol Metab       Date:  1972-05       Impact factor: 5.958

5.  The effect of quinolinic acid on the content and distribution of hepatic metabolites.

Authors:  O S Spydervold; N Zaheer-Baquer; P McLean; A L Greenbaum
Journal:  Arch Biochem Biophys       Date:  1974-10       Impact factor: 4.013

6.  Fuels, hormones, and liver metabolism at term and during the early postnatal period in the rat.

Authors:  J R Girard; G S Cuendet; E B Marliss; A Kervran; M Rieutort; R Assan
Journal:  J Clin Invest       Date:  1973-12       Impact factor: 14.808

7.  Effects of exogenous hormones and glucose on plasma levels and hepatic metabolism of amino acids in the fetus and in the newborn rat.

Authors:  J R Girard; I Guillet; J Marty; R Assan; E B Marliss
Journal:  Diabetologia       Date:  1976-08       Impact factor: 10.122

8.  Glycerol metabolism in the neonatal rat.

Authors:  R G Vernon; D G Walker
Journal:  Biochem J       Date:  1970-07       Impact factor: 3.857

9.  3-mercaptopicolinic acid, an inhibitor of gluconeogenesis.

Authors:  N W DiTullio; C E Berkoff; B Blank; V Kostos; E J Stack; H L Saunders
Journal:  Biochem J       Date:  1974-03       Impact factor: 3.857

10.  Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats.

Authors:  M A Page; H A Krebs; D H Williamson
Journal:  Biochem J       Date:  1971-01       Impact factor: 3.857
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  9 in total

1.  Enhancement of the anti-anabolic response to adenosine 3':5'-cyclic monophosphate during development. The inhibition of hepatic protein synthesis.

Authors:  A Klaipongpan; D P Bloxham; M Akhtar
Journal:  Biochem J       Date:  1977-11-15       Impact factor: 3.857

2.  Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo.

Authors:  Christopher J Ramnanan; Dale S Edgerton; Noelia Rivera; Jose Irimia-Dominguez; Ben Farmer; Doss W Neal; Margaret Lautz; E Patrick Donahue; Catalina M Meyer; Peter J Roach; Alan D Cherrington
Journal:  Diabetes       Date:  2010-02-25       Impact factor: 9.461

3.  Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats.

Authors:  P Ferré; P Satabin; L El Manoubi; S Callikan; J Girard
Journal:  Biochem J       Date:  1981-11-15       Impact factor: 3.857

4.  Evidence for the participation of aspartate aminotransferase in hepatic glucose synthesis in the suckling newborn rat.

Authors:  P Ferré; D H Williamson
Journal:  Biochem J       Date:  1978-10-15       Impact factor: 3.857

5.  The metabolic effects of sodium dichloroacetate in the suckling newborn rat.

Authors:  J P Pegorier; P Ferré; A Leturque; J Girard
Journal:  Diabetologia       Date:  1978-12       Impact factor: 10.122

6.  The early development of white adipose tissue. Effects of litter size on the lipoprotein lipase activity of four adipose-tissue depots, serum immunoreactive insulin and tissue cellularity during the first four weeks of life in the rat.

Authors:  A Cryer; H M Jones
Journal:  Biochem J       Date:  1979-03-15       Impact factor: 3.857

7.  The effects of inhibition of fatty acid oxidation in suckling newborn rats.

Authors:  J P Pégorier; P Ferré; J Girard
Journal:  Biochem J       Date:  1977-09-15       Impact factor: 3.857

8.  Lactate as an oxidizable substrate for rat brain in vitro during the perinatal period.

Authors:  C Arizmendi; J M Medina
Journal:  Biochem J       Date:  1983-08-15       Impact factor: 3.857

9.  Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.

Authors:  Dale S Edgerton; Christopher J Ramnanan; Carrie A Grueter; Kathryn M S Johnson; Margaret Lautz; Doss W Neal; Phillip E Williams; Alan D Cherrington
Journal:  Diabetes       Date:  2009-09-15       Impact factor: 9.461
  9 in total

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