Literature DB >> 577680

Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential.

M K Johnson.   

Abstract

The assay of neurotoxic esterase (NTE) in brains taken from dosed hens enables potential neurotoxicity of organophosphate pesticides, plasticers, etc. to be assessed. The original assay [Johnson, M.K. Biochem. J. 114, 711-717 (1969)] has been simplified to eliminate centrifugation and transfer steps and both the selectivity and the sensitivity have been increased. The procedures necessary to obtain stable reagent stocks are described.

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Year:  1977        PMID： 577680     DOI： 10.1007/bf00293860

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  3 in total

Review 1.  The delayed neuropathy caused by some organophosphorus esters: mechanism and challenge.

Authors:  M K Johnson
Journal:  CRC Crit Rev Toxicol       Date:  1975-06

Review 2.  Organophosphorus esters causing delayed neurotoxic effects: mechanism of action and structure activity studies.

Authors:  M K Johnson
Journal:  Arch Toxicol       Date:  1975-12-18       Impact factor: 5.153

3.  The delayed neurotoxic effect of some organophosphorus compounds. Identification of the phosphorylation site as an esterase.

Authors:  M K Johnson
Journal:  Biochem J       Date:  1969-10       Impact factor: 3.857
  3 in total
  53 in total

1.  Molecular cloning and expression of the C-terminal domain of mouse NTE-related esterase.

Authors:  Ping-An Chang; Ding-Xin Long; Yi-Jun Wu
Journal:  Mol Cell Biochem       Date:  2007-08-03       Impact factor: 3.396

2.  Simplified models to analyse time- and dose-dependent responses of populations to toxicants.

Authors:  Francisco Sánchez-Bayo; Kouichi Goka
Journal:  Ecotoxicology       Date:  2007-07-11       Impact factor: 2.823

Review 3.  The metabolic serine hydrolases and their functions in mammalian physiology and disease.

Authors:  Jonathan Z Long; Benjamin F Cravatt
Journal:  Chem Rev       Date:  2011-06-23       Impact factor: 60.622

4.  Anomalous biochemical responses in tests of the delayed neuropathic potential of methamidophos (O,S-dimethyl phosphorothioamidate), its resolved isomers and of some higher O-alkyl homologues.

Authors:  M K Johnson; E Vilanova; D J Read
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

5.  Protein domains, catalytic activity, and subcellular distribution of mouse NTE-related esterase.

Authors:  Ping-An Chang; Zhan-Xiang Wang; Ding-Xin Long; Wen-Zhen Qin; Yi-Jun Wu
Journal:  Mol Cell Biochem       Date:  2010-01-08       Impact factor: 3.396

Review 6.  Prophylaxis and the mechanism for the initiation of organophosphorous compound-induced delayed neurotoxicity.

Authors:  C D Carrington
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153

7.  Interaction of methamidophos with hen and human acetylcholinesterase and neuropathy target esterase.

Authors:  M Bertolazzi; S Caroldi; A Moretto; M Lotti
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

8.  Clinical and toxicological investigations of a case of delayed neuropathy in man after acute poisoning by an organophosphorus pesticide.

Authors:  R Hierons; M K Johnson
Journal:  Arch Toxicol       Date:  1978-08-09       Impact factor: 5.153

9.  Repeated small doses of a neurotoxic organophosphate. Monitoring of neurotoxic esterase in brain and spinal cord.

Authors:  M Lotti; M K Johnson
Journal:  Arch Toxicol       Date:  1980-10       Impact factor: 5.153

10.  Neurotoxic esterase. Identification of two isoenzymes in hen brain.

Authors:  J M Chemnitius; K H Haselmeyer; R Zech
Journal:  Arch Toxicol       Date:  1983-07       Impact factor: 5.153
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