Literature DB >> 21696217

The metabolic serine hydrolases and their functions in mammalian physiology and disease.

Jonathan Z Long1, Benjamin F Cravatt.   

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Year:  2011        PMID: 21696217      PMCID: PMC3192302          DOI: 10.1021/cr200075y

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


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  605 in total

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4.  A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS).

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5.  Identification of functional domains of rat intestinal phospholipase B/lipase. Its cDNA cloning, expression, and tissue distribution.

Authors:  H Takemori; F N Zolotaryov; L Ting; T Urbain; T Komatsubara; O Hatano; M Okamoto; H Tojo
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8.  A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein.

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9.  Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma.

Authors:  D M Stafforini; T Numao; A Tsodikov; D Vaitkus; T Fukuda; N Watanabe; N Fueki; T M McIntyre; G A Zimmerman; S Makino; S M Prescott
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10.  Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV.

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Journal:  Gene       Date:  2002-10-16       Impact factor: 3.688

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  142 in total

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2.  A solvent-free delipidation method for functional validation of lipases.

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3.  How chemoproteomics can enable drug discovery and development.

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4.  Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome.

Authors:  Catherine Bélanger; Félix-Antoine Bérubé-Simard; Elizabeth Leduc; Guillaume Bernas; Philippe M Campeau; Seema R Lalani; Donna M Martin; Stephanie Bielas; Amanda Moccia; Anshika Srivastava; David W Silversides; Nicolas Pilon
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5.  Synthetic Fluorogenic Peptides Reveal Dynamic Substrate Specificity of Depalmitoylases.

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6.  Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides.

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Review 7.  Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom.

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8.  Application of activity-based protein profiling to study enzyme function in adipocytes.

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9.  Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling.

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10.  Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9.

Authors:  Xiaodan Liu; Melissa Dix; Anna E Speers; Daniel A Bachovchin; Andrea M Zuhl; Benjamin F Cravatt; Thomas J Kodadek
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