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Literature DB >> 573891

Interaction of DNA with a porphyrin ligand: evidence for intercalation.

R J Fiel, J C Howard, E H Mark, N Datta Gupta.

Abstract

The porphyrin photosensitizer, meso-Tetra (4-N-methylpyridyl) porphine tetraperchlorate binds to calf thymus DNA by intercalation and by external electrostatic association. This was concluded from the results of measruements involving Scatchard analysis, viscometry, thermal denaturation, and circular dichroism.

Entities: Species

Mesh：

Substances：
Porphyrins
DNA

Year: 1979 PMID： 573891 PMCID： PMC327919 DOI： 10.1093/nar/6.9.3093

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

14 in total

1. Stereochemical aspects of the interaction between steroidal diamines and DNA.

Authors: M J Waring; S M Henley
Journal: Nucleic Acids Res Date: 1975-04 Impact factor: 16.971

2. Studies on the Methyl Green-DNA complex and its dissociation by drugs.

Authors: A K Krey; F E Hahn
Journal: Biochemistry Date: 1975-11-18 Impact factor: 3.162

3. Conformational flexibility in DNA structure as revealed by structural studies of drug intercalation and its broader implications in understanding the organization of DNA in chromatin.

Authors: H M Sobell; B S Reddy; K K Bhandary; S C Jain; T D Sakore; T P Seshadri
Journal: Cold Spring Harb Symp Quant Biol Date: 1978

4. Comparative binding study of the interaction of quinacrine and ethidium bromide with DNA and nucleohistone.

Authors: J Bontemps; E Fredericq
Journal: Biophys Chem Date: 1974-06 Impact factor: 2.352

5. Studies of the binding of actinomycin and related compounds to DNA.

Authors: W Müller; D M Crothers
Journal: J Mol Biol Date: 1968-07-28 Impact factor: 5.469

6. Aggregation of properties of water-soluble porphyrins.

Authors: R F Pasternack
Journal: Ann N Y Acad Sci Date: 1973 Impact factor: 5.691

7. Sodium-23 NMR studies of cation-DNA interactions.

Authors: C F Anderson; M T Record; P A Hart
Journal: Biophys Chem Date: 1978-01 Impact factor: 2.352

8. Visualization of drug-nucleic acid interactions at atomic resolution. III. Unifying structural concepts in understanding drug-DNA interactions and their broader implications in understanding protein-DNA interactions.

Authors: H M Sobell; C C Tsai; S C Jain; S G Gilbert
Journal: J Mol Biol Date: 1977-08-15 Impact factor: 5.469

9. Formaldehyde as a probe of DNA structure. I. Reaction with exocyclic amino groups of DNA bases.

Authors: J D McGhee; P H von Hippel
Journal: Biochemistry Date: 1975-03-25 Impact factor: 3.162

10. Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex.

Authors: T D Sakore; S C Jain; C C Tsai; H M Sobell
Journal: Proc Natl Acad Sci U S A Date: 1977-01 Impact factor: 11.205

34 in total

1. Photosensitivity and lymphoma.

Authors: D P Busuttil; M G Davies; J A Copplestone; M D Hamon; A G Prentice
Journal: Postgrad Med J Date: 1997-07 Impact factor: 2.401

2. Assessment of the photosensitization properties of cationic porphyrins in interaction with DNA nucleotide pairs.

Authors: Gloria I Cárdenas-Jirón; Luis Cortez
Journal: J Mol Model Date: 2013-04-14 Impact factor: 1.810

3. Binding of tetrakis(pyrazoliumyl)porphyrin and its copper(II) and zinc(II) complexes to poly(dG-dC)2 and poly(dA-dT)2.

Authors: Daryono H Tjahjono; Rahmana E Kartasasmita; As'ari Nawawi; Shunsuke Mima; Takehiro Akutsu; Naoki Yoshioka; Hidenari Inoue
Journal: J Biol Inorg Chem Date: 2006-04-22 Impact factor: 3.358

Interaction of DNA with a porphyrin ligand: evidence for intercalation.

1. Stereochemical aspects of the interaction between steroidal diamines and DNA.

2. Studies on the Methyl Green-DNA complex and its dissociation by drugs.

3. Conformational flexibility in DNA structure as revealed by structural studies of drug intercalation and its broader implications in understanding the organization of DNA in chromatin.

4. Comparative binding study of the interaction of quinacrine and ethidium bromide with DNA and nucleohistone.

5. Studies of the binding of actinomycin and related compounds to DNA.

6. Aggregation of properties of water-soluble porphyrins.

7. Sodium-23 NMR studies of cation-DNA interactions.

8. Visualization of drug-nucleic acid interactions at atomic resolution. III. Unifying structural concepts in understanding drug-DNA interactions and their broader implications in understanding protein-DNA interactions.

9. Formaldehyde as a probe of DNA structure. I. Reaction with exocyclic amino groups of DNA bases.

10. Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex.

1. Photosensitivity and lymphoma.

2. Assessment of the photosensitization properties of cationic porphyrins in interaction with DNA nucleotide pairs.

3. Binding of tetrakis(pyrazoliumyl)porphyrin and its copper(II) and zinc(II) complexes to poly(dG-dC)2 and poly(dA-dT)2.

4. Molecular modelling of the interactions of tetra-(4-N-methylpyridyl) porphin with TA and CG sites on DNA.

5. The influence of ionic strength on the binding of a water soluble porphyrin to nucleic acids.

6. DNA sequence preferences for an intercalating porphyrin compound revealed by footprinting.

7. A three-layer ONIOM model for the outside binding of cationic porphyrins and nucleotide pair DNA.

8. Major versus minor groove DNA binding of a bisarginylporphyrin hybrid molecule: a molecular mechanics investigation.

9. "One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.

10. Chiral probes for the handedness of DNA helices: enantiomers of tris(4,7-diphenylphenanthroline)ruthenium(II).