Literature DB >> 677874

Production of cyclochlorotine and a new metabolite, simatoxin, by Penicillium islandicum Sopp.

A C Ghosh, A Manmade, J M Townsend, A Bousquet, J F Howes, A L Demain.   

Abstract

Production of the hepatotoxin cyclochlorotine by Penicillium islandicum was studied under a variety of fermentation conditions. The best system for production was agitated red wheat. A thin-layer chromatographic method was developed for the detection of this cyclic polypeptide. These experiments have resulted in the isolation of a new toxic metabolite, which we call simatoxin.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 677874      PMCID： PMC242987          DOI： 10.1128/aem.35.6.1074-1078.1978

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  9 in total

Review 1.  Mycotoxins.

Authors:  G N Wogan
Journal:  Annu Rev Pharmacol       Date:  1975       Impact factor: 13.820

2.  [Study of the toxic principle in yellow rice].

Authors:  T TATSUNO; M TSUKIOKA; Y SAKAI; Y SUZUKI; Y ASAMI
Journal:  Pharm Bull       Date:  1955-12

3.  Chronic toxicity and carcinogenicity in mice of the purified mycotoxins, luteoskyrin and cyclochlorotine.

Authors:  K Uraguchi; M Saito; Y Noguchi; K Takahashi; M Enomoto
Journal:  Food Cosmet Toxicol       Date:  1972-04

4.  Some recent studies on the metabolites of fungi and lichens.

Authors:  S Shibata
Journal:  Pure Appl Chem       Date:  1973       Impact factor: 2.453

5.  Biotechnology report. Solid state fermentations.

Authors:  C W Hesseltine
Journal:  Biotechnol Bioeng       Date:  1972-07       Impact factor: 4.530

6.  The bioassay of aflatoxins and related substances with Bacillus megaterium spores and chick embryos.

Authors:  A Jayaraman; E J Herbst; M Ikawa
Journal:  J Am Oil Chem Soc       Date:  1968-10       Impact factor: 1.849

7.  Chemical determination of the chlorine-containing peptide, a hepatotoxic mycotoxin of Penicillium islandicum Sopp.

Authors:  I Ishikawa; Y Ueno; H Tsunoda
Journal:  J Biochem       Date:  1970-06       Impact factor: 3.387

8.  Production of the hepatotoxic chlorine-containing peptide by Penicillium islandicum Sopp.

Authors:  K Ishii; Y Ueno
Journal:  Appl Microbiol       Date:  1973-09

9.  Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp.

Authors:  A C Ghosh; A Manmade; B Kobbe; J M Townsend; A L Demain
Journal:  Appl Environ Microbiol       Date:  1978-03       Impact factor: 4.792
  9 in total
  3 in total

1.  Polyphasic taxonomy of the genus Talaromyces.

Authors:  N Yilmaz; C M Visagie; J Houbraken; J C Frisvad; R A Samson
Journal:  Stud Mycol       Date:  2014-06       Impact factor: 16.097

2.  A convenient thin layer chromatographic method for the detection of cyclochlorotine and simatoxin, toxins from Penicillium islandicum Sopp.

Authors:  A C Ghosh; A Manmade; A Bousquet; J M Townsend; A L Demain
Journal:  Experientia       Date:  1978-06-15

3.  Solid state fermentation for cephalosporin production by Streptomyces clavuligerus and Cephalosporium acremonium.

Authors:  M F Jermini; A L Demain
Journal:  Experientia       Date:  1989-12-01
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.