Literature DB >> 563063

Genes for gamma-globin in human adult erythroid DNA.

G J Mitchell, R Williamson.   

Abstract

Purified gamma-globin specific complementary DNA has been used to demonstrate the presence of the gene for gamma-globin in DNA from human adult red blood cells. This finding sheds doubt on any theory involving looping-out excision of genes to explain the switch over from synthesis of gamma-globin to beta-globin at birth.

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Year:  1977        PMID： 563063      PMCID： PMC342671          DOI： 10.1093/nar/4.10.3557

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  15 in total

1.  LINKAGE OF THE BETA-CHAIN AND DELTA-CHAIN STRUCTURAL GENES OF HUMAN HEMOGLOBINS.

Authors:  B F HORTON; T H HUISMAN
Journal:  Am J Hum Genet       Date:  1963-12       Impact factor: 11.025

2.  FURTHER EVIDENCE OF LINKAGE BETWEEN THE BETA AND DELTA LOCI GOVERNING HUMAN HEMOGLOBIN AND THE POPULATION DYNAMICS OF LINKED GENES.

Authors:  S H BOYER; D L RUCKNAGEL; D J WEATHERALL; E J WATSON-WILLIAMS
Journal:  Am J Hum Genet       Date:  1963-12       Impact factor: 11.025

3.  The fusion of two peptide chains in hemoglobin Lepore and its interpretation as a genetic deletion.

Authors:  C BAGLIONI
Journal:  Proc Natl Acad Sci U S A       Date:  1962-11-15       Impact factor: 11.205

4.  A direct estimate of the number of human gamma-globin genes.

Authors:  J Old; J B Clegg; D J Weatherall; S Ottolenghi; P Comi; B Giglioni; J Mitchell; P Tolstoshev; R Williamson
Journal:  Cell       Date:  1976-05       Impact factor: 41.582

5.  Stability of the individual globin genes during erythroid differentiation.

Authors:  E Benz; P Turner; J Barker; A Nienhuis
Journal:  Science       Date:  1977-06-10       Impact factor: 47.728

6.  Hemoglobin ontogenesis: test of the gene excision hypothesis.

Authors:  T h Papayannopoulou; P E Nute; G Stamatoyannopoulos; T C McGuire
Journal:  Science       Date:  1977-06-10       Impact factor: 47.728

7.  Molecular weight determination of nucleic acids by gel electrophoresis in non-aqueous solution.

Authors:  D Z Staynov; J C Pinder; W B Gratzer
Journal:  Nat New Biol       Date:  1972-01-26

8.  Kinetic studies of gene frequency. I. Use of a DNA copy of reticulocyte 9 S RNA to estimate globin gene dosage in mouse tissues.

Authors:  P R Harrison; G D Birnie; A Hell; S Humphries; B D Young; J Paul
Journal:  J Mol Biol       Date:  1974-04-25       Impact factor: 5.469

9.  DNA sequences neighboring the duck hemoglobin genes.

Authors:  J O Bishop; K B Freeman
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1974

10.  Delta-beta-thalassemia is due to a gene deletion.

Authors:  S Ottolenghi; P Comi; B Giglioni; P Tolstoshev; W G Lanyon; G J Mitchell; R Williamson; G Russo; S Musumeci; G Schillro; G A Tsistrakis; S Charache; W G Wood; J B Clegg; D J Weatherall
Journal:  Cell       Date:  1976-09       Impact factor: 41.582
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  1 in total

1.  Structure of recombinant plasmids containing synthetic human foetal globin gene sequences.

Authors:  P Humphries; L W Coggins; R W Old; G J Mitchell; C Coleclough; J Paul
Journal:  Mol Gen Genet       Date:  1978-09-20
  1 in total

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