Literature DB >> 860136

Stability of the individual globin genes during erythroid differentiation.

E Benz, P Turner, J Barker, A Nienhuis.   

Abstract

The genes of sheep betaA, betaC, and gamma globin were all present in DNA from erythroid cells which synthesized only betaC globin. Similarly, selective excision of non-expressed genes was shown not to occur during human erythroid differentiation. In contrast, evolutionary deletion of the betaC gene accounts for the inability of many sheep to make this globin.

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Year:  1977        PMID: 860136     DOI: 10.1126/science.860136

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  7 in total

1.  Hemoglobin F synthesis in vitro: evidence for control at the level of primitive erythroid stem cells.

Authors:  T Papayannopoulou; M Brice; G Stamatoyannopoulos
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

2.  Hemoglobin switching in sheep and goats: induction of hemoglobin C synthesis in cultures of sheep fetal erythroid cells.

Authors:  J E Barker; J E Pierce; B C Kefauver; A W Nienhuis
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

3.  Differences in the number of embryonic and pseudo-beta-globin genes between HbA and HbB sheep.

Authors:  A Rando; P Di Gregorio; P Masina
Journal:  Biochem Genet       Date:  1989-02       Impact factor: 1.890

4.  Is histone H5 present in mammals?

Authors:  J Zlatanova
Journal:  Mol Biol Rep       Date:  1981-08-14       Impact factor: 2.316

5.  Genes for gamma-globin in human adult erythroid DNA.

Authors:  G J Mitchell; R Williamson
Journal:  Nucleic Acids Res       Date:  1977-10       Impact factor: 16.971

6.  Hemoglobin switching in sheep: only the gamma gene is in the active conformation in fetal liver but all the beta and gamma genes are in the active conformation in bone marrow.

Authors:  N S Young; E J Benz; J A Kantor; P Kretschmer; A W Nienhuis
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

7.  A comparison of the beta A-and beta B-globin gene clusters of sheep.

Authors:  K J Garner; J B Lingrel
Journal:  J Mol Evol       Date:  1989-03       Impact factor: 2.395

  7 in total

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