Literature DB >> 103076

Formation and characterization of antibody against 2'-(5"-phosphoribosyl)-5' AMP, the monomer form of poly(adenosine diphosphate ribose).

H Sakura, M Miwa, Y Kanai, T Matsushima, T Sugimura.   

Abstract

Specific antibody against 2'-(5"-phosphoribosyl)-5'AMP (PR-AMP), a monomer of poly(adenosine diphosphate ribose) (poly(ADP-Rib)), was produced by immunizing a rabbit with PR-AMP coupled to bovine serum albumin (BSA). Antibody against PR-AMP was purified 53-fold from serum by (NH4) 2SO4 precipitation, and BSA-Sepharose 4B, DEAE-cellulose and (PR-AMP)-BSA-Sepharose 4B column chromatographies. Inhibition experiments show that the adenine ring, 5'-phosphate residue and ribose-ribose bond of PR-AMP were essential for the antigenic determinant of PR-AMP. Anti PR-AMP antibody bound, not only with PR-AMP, but also with poly(ADP-Rib) of various chain lengths, while anti poly(ADP-Rib) antibody bound with poly(ADP-Rib) but not with PR-AMP.

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Year:  1978        PMID： 103076      PMCID： PMC342731          DOI： 10.1093/nar/5.11.4025

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  22 in total

1.  ANTIBODIES SPECIFIC FOR RIBONUCLEOSIDES AND RIBONUCLEOTIDES AND THEIR REACTION WITH DNA.

Authors:  B F ERLANGER; S M BEISER
Journal:  Proc Natl Acad Sci U S A       Date:  1964-07       Impact factor: 11.205

Review 2.  Poly(ADP-ribose) and ADP-ribosylation of proteins.

Authors:  O Hayaishi; K Ueda
Journal:  Annu Rev Biochem       Date:  1977       Impact factor: 23.643

Review 3.  Poly(ADP-ribose) and ADP-ribosylation of proteins.

Authors:  H Hilz; P Stone
Journal:  Rev Physiol Biochem Pharmacol       Date:  1976       Impact factor: 5.545

4.  Studies on anti-poly(adenosine diphosphate ribose) antibody.

Authors:  Y Kanai; M Miwa; T Matsushima; T Sugimura
Journal:  Biochem Biophys Res Commun       Date:  1974-07-10       Impact factor: 3.575

5.  Changes in poly(adenosine diphosphate-ribose) and poly(adenosine diphosphate-ribose) polymerase in synchronous HeLa cells.

Authors:  W R Kidwell; M G Mage
Journal:  Biochemistry       Date:  1976-03-23       Impact factor: 3.162

6.  Characterization of antibodies specific for N6-methyladenosine and for 7-methylguanosine.

Authors:  T W Munns; M K Liszewski; H F Sims
Journal:  Biochemistry       Date:  1977-05-17       Impact factor: 3.162

7.  Ribosome structure: localization of N6,N6-dimethyladenosine by electron microscopy of a ribosome-antibody complex.

Authors:  S M Politz; D G Glitz
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

8.  Separation of oligo(adenosine diphosphate ribose) fractions with various chain lengths and terminal structures.

Authors:  M Tanaka; M Miwa; K Hayashi; K Kubota; T Matsushima
Journal:  Biochemistry       Date:  1977-04-05       Impact factor: 3.162

9.  Natural occurence of a biopolymer, poly (adenosine diphosphate ribose).

Authors:  H Sakura; M Miwa; M Tanaka; Y Kanai; T Shimada; T Matsushima; T Sugimura
Journal:  Nucleic Acids Res       Date:  1977-08       Impact factor: 16.971

10.  Antibodies specific to a deoxyribodinucleotide sequence.

Authors:  S A Khan; M Z Humayun; T M Jacob
Journal:  Nucleic Acids Res       Date:  1977-09       Impact factor: 16.971
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  3 in total

1.  Comparative studies on antibodies to poly(ADP-ribose) in rabbits and patients with systemic lupus erythematosus.

Authors:  Y Kanai; T Sugimura
Journal:  Immunology       Date:  1981-05       Impact factor: 7.397

2.  Mono- and poly-ADP-ribosylation of proteins in mouse kidney after castration and testosterone treatment.

Authors:  A Gartemann; R Bredehorst; K Wielckens; W H Strätling; H Hilz
Journal:  Biochem J       Date:  1981-07-15       Impact factor: 3.857

3.  Development and characterization of new tools for detecting poly(ADP-ribose) in vitro and in vivo.

Authors:  Sridevi Challa; Keun W Ryu; Amy L Whitaker; Jonathan C Abshier; Cristel V Camacho; W Lee Kraus
Journal:  Elife       Date:  2022-04-27       Impact factor: 8.713
  3 in total

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