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Literature DB >> 560186

Immunological relationships and a genetic interpretation of major and minor acidic proteins in human parotid saliva.

Abstract

Isoelectric focusing was performed on parotid salivas selected for their electrophoretic phenotypes of proline-rich acidic salivary proteins. Fractions encompassing narrow pH regions were pooled and examined by polyacrylamide gel electrophoresis. Isoelectric focusing yielded partial purification of major and minor acidic proline-rich proteins which were subsequently compared by immunoelectrophoresis and double immunodiffusion against goat anti-human parotid saliva. Cross-reactivity without spurring between all fractions containing major Pr proteins in both immunoelectrophoresis and double immunodiffusion suggests that these proteins are immunologically very similar or identical.

Entities: Chemical Disease Species

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Year: 1977 PMID： 560186 DOI： 10.1007/bf00520197

Source DB: PubMed Journal: Biochem Genet ISSN： 0006-2928 Impact factor: 1.890

14 in total

1. Fractionation of human parotid salivary proteins and the isolation of an histidine-rich acidic peptide which shows high affinity for hydroxyapatite surfaces.

Authors: D I Hay
Journal: Arch Oral Biol Date: 1975-09 Impact factor: 2.633

2. An improved method for the detection of anionic polymorphic proteins in human saliva on polyacrylamide slab gels.

Authors: R D Friedman; R Allushuski
Journal: Anal Biochem Date: 1975-05-12 Impact factor: 3.365

3. Proline-rich proteins from human parotid saliva. I. Isolation and partial characterization.

Authors: F G Oppenheim; D I Hay; C Franzblau
Journal: Biochemistry Date: 1971-11 Impact factor: 3.162

4. Genetic polymorphism of human salivary proline-rich proteins: further genetic analysis.

Authors: E A Azen; C L Denniston
Journal: Biochem Genet Date: 1974-08 Impact factor: 1.890

5. The isolation from human parotid saliva of a further group of proline-rich proteins.

Authors: D I Hay; F G Oppenheim
Journal: Arch Oral Biol Date: 1974-08 Impact factor: 2.633

6. Genetic polymorphism of proline-rich human salivary proteins.

Authors: E A Azen; F G Oppenheim
Journal: Science Date: 1973-06-08 Impact factor: 47.728

7. Purification and partial characterization of four proteins from human parotid saliva.

Authors: A Bennick; G E Connell
Journal: Biochem J Date: 1971-07 Impact factor: 3.857

8. [Amino acid composition of 5 human salivary isoamylases].

Authors: A Carlier; A Hayem; M Bonte; J Andjic; R Havez
Journal: C R Acad Hebd Seances Acad Sci D Date: 1970-12-09

9. [Isolation of salivary amylase isoenzymes by isoelectrofocusing].

Authors: J Andjic; A Hayem; A Carlier; M Bonte
Journal: C R Acad Hebd Seances Acad Sci D Date: 1970-01-12

10. Genetic studies of human acidic salivary protein (Pa).

Authors: R D Friedman; A D Merritt; M L Rivas
Journal: Am J Hum Genet Date: 1975-05 Impact factor: 11.025

8 in total

1. Description of a genetic polymorphism of a human proline-rich salivary protein, Pc, and its relationship to other proteins in the salivary protein complex (SPC).

Authors: R C Karn; P A Goodman; P L Yu
Journal: Biochem Genet Date: 1985-02 Impact factor: 1.890

2. Genetic polymorphism of CON 1 and CON 2 salivary proteins detected by immunologic and concanavalin A reactions on nitrocellulose with linkage of CON 1 and CON 2 genes to the SPC (salivary protein gene complex).

Authors: E A Azen; P L Yu
Journal: Biochem Genet Date: 1984-02 Impact factor: 1.890

3. Genetic polymorphism of PIF (parotid isoelectric focusing variant) proteins with linkage to the PPP (parotid proline-rich protein) gene complex.

Authors: E A Azen; C Denniston
Journal: Biochem Genet Date: 1981-06 Impact factor: 1.890

7. Polymorphism of Ps (parotid size variant) and detection of a protein (PmS) related to the Pm (parotid middle band) system with genetic linkage of Ps and Pm to Gl, Db, and Pr genetic determinants.

Authors: E A Azen; C Denniston
Journal: Biochem Genet Date: 1980-06 Impact factor: 1.890

8. Linkage relationships and multipoint mapping of the human parotid salivary proteins (Pr, Pa, Db).

Authors: P L Yu; R C Karn; A D Merritt; E A Azen; P M Conneally
Journal: Am J Hum Genet Date: 1980-07 Impact factor: 11.025