Literature DB >> 540000

Human salivary proline-rich (Pr) proteins: a posttranslational derivation of the phenotypes.

R C Karn, R D Friedman, A D Merritt.   

Abstract

The acidic proline-rich proteins (Pr) showing genetic polymorphism were purified from human parotid salivas by gel filtration and ion exchange chromatography. Molecular weight determinations, amino acid composition analyses, and polypeptide mapping experiments indicate that the Pr 3 protein is a fragment of the Pr 1 protein. Studies of a parotid saliva factor capable of converting Pr 1 to Pr 3 and Pr 2 to Pr 4 indicate that Pr 3 and Pr 4 are generated from Pr 1 and Pr 2, respectively. Evidence suggests that the converting factor is a protease capable of posttranslationally cleaving Pr 1 and Pr 2, the primary or derived products of alleles Pr1 and Pr2.

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Year:  1979        PMID： 540000     DOI： 10.1007/BF00504345

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  26 in total

1.  Properties of salivary basic proteins showing polymorphism.

Authors:  E A Azen
Journal:  Biochem Genet       Date:  1973-05       Impact factor: 1.890

2.  The isolation from human parotid saliva of a further group of proline-rich proteins.

Authors:  D I Hay; F G Oppenheim
Journal:  Arch Oral Biol       Date:  1974-08       Impact factor: 2.633

3.  Genetic polymorphism of proline-rich human salivary proteins.

Authors:  E A Azen; F G Oppenheim
Journal:  Science       Date:  1973-06-08       Impact factor: 47.728

4.  Hydrolysis of proteins with p-toluenesulfonic acid. Determination of tryptophan.

Authors:  T Y Liu; Y H Chang
Journal:  J Biol Chem       Date:  1971-05-10       Impact factor: 5.157

5.  Immunological relationships and a genetic interpretation of major and minor acidic proteins in human parotid saliva.

Authors:  R D Friedman; R C Karn
Journal:  Biochem Genet       Date:  1977-06       Impact factor: 1.890

6.  Linkage relationships of the proline-rich salivary proteins (Pr, Pa, Db).

Authors:  P L Yu; R C Schwartz; A D Merritt; E A Azen; M L Rivas; R C Karn; M A Craft
Journal:  Cytogenet Cell Genet       Date:  1978

7.  Phenanthrenequinone as an analytical reagent for arginine and other monosubstituted guanidines.

Authors:  S Yamada; H Itano
Journal:  Biochim Biophys Acta       Date:  1966-12-28

8.  Genetic studies of human acidic salivary protein (Pa).

Authors:  R D Friedman; A D Merritt; M L Rivas
Journal:  Am J Hum Genet       Date:  1975-05       Impact factor: 11.025

9.  The binding of calcium to a salivary phosphoprotein, protein A, common to human parotid and submandibular secretions.

Authors:  A Bennick
Journal:  Biochem J       Date:  1976-04-01       Impact factor: 3.857

10.  Human saliva kallikrein. Biological properties of saliva kallikrein isolated by use of affinity chromatography.

Authors:  T Modéer
Journal:  Acta Odontol Scand       Date:  1977       Impact factor: 2.331
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  12 in total

1.  The human salivary protein complex (SPC): a large block of related genes.

Authors:  P A Goodman; P L Yu; E A Azen; R C Karn
Journal:  Am J Hum Genet       Date:  1985-07       Impact factor: 11.025

2.  Inheritance of the human salivary proline-rich proteins: a reinterpretation in terms of six loci forming two subfamilies.

Authors:  N Maeda
Journal:  Biochem Genet       Date:  1985-06       Impact factor: 1.890

3.  Description of a genetic polymorphism of a human proline-rich salivary protein, Pc, and its relationship to other proteins in the salivary protein complex (SPC).

Authors:  R C Karn; P A Goodman; P L Yu
Journal:  Biochem Genet       Date:  1985-02       Impact factor: 1.890

4.  The primary structures of six human salivary acidic proline-rich proteins (PRP-1, PRP-2, PRP-3, PRP-4, PIF-s and PIF-f).

Authors:  D I Hay; A Bennick; D H Schlesinger; K Minaguchi; G Madapallimattam; S K Schluckebier
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

5.  Isolation and partial characterization of a polymorphic protein (Pm) in human parotid saliva.

Authors:  K Minaguchi; S Ikemoto; K Suzuki
Journal:  Biochem Genet       Date:  1981-06       Impact factor: 1.890

6.  Genetic polymorphism of PIF (parotid isoelectric focusing variant) proteins with linkage to the PPP (parotid proline-rich protein) gene complex.

Authors:  E A Azen; C Denniston
Journal:  Biochem Genet       Date:  1981-06       Impact factor: 1.890

7.  The role of glandular kallikrein in the formation of a salivary proline-rich protein A by cleavage of a single bond in salivary protein C.

Authors:  R S Wong; G Madapallimattam; A Bennick
Journal:  Biochem J       Date:  1983-04-01       Impact factor: 3.857

8.  Sex-limited genetic variation in a mouse salivary protein.

Authors:  R C Karn; S R Dlouhy; K R Springer; J P Hjorth; J T Nielsen
Journal:  Biochem Genet       Date:  1982-06       Impact factor: 1.890

9.  Expression of human salivary protein genes.

Authors:  P W Mamula; D J Morley; S H Larsen; R C Karn
Journal:  Biochem Genet       Date:  1988-02       Impact factor: 1.890

Review 10.  Salivary proline-rich proteins.

Authors:  A Bennick
Journal:  Mol Cell Biochem       Date:  1982-06-11       Impact factor: 3.396
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