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Literature DB >> 5551273

Paracetamol and renal damage.

O M Edwards, P Edwards, E C Huskisson, R T Taylor.

Abstract

Renal function was assessed in 18 patients who had consumed 2 to 30 kg of paracetamol. No relationship was found between the total amount of paracetamol taken and any aspect of renal function studied. No patient had clinically significant renal impairment. Thirteen of the patients showed no significant deterioration of renal function over a period of about one year during which they consumed an additional mean 2 kg of paracetamol.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1971 PMID： 5551273 PMCID： PMC1795531 DOI： 10.1136/bmj.2.5753.87

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

9 in total

1. Renal concentrating defect in Sjogren's syndrome.

Authors: M KAHN; A D MERRITT; M J WOHL; J ORLOFF
Journal: Ann Intern Med Date: 1962-06 Impact factor: 25.391

2. Renal tubular acidosis, glomerulonephritis and immunologic factors in Sjögren's syndrome.

Authors: N Talal; E Zisman; P H Schur
Journal: Arthritis Rheum Date: 1968-12

3. Phenacetin nephropathy.

Authors: D Kerr
Journal: Br Med J Date: 1970-11-07

4. Paracetamol and the kidney.

Authors: D M Krikler
Journal: Br Med J Date: 1967-06-03

5. Phenacetin nephropathy, with particular reference to the effect of surgery.

Authors: K G Koutsaimanis; H E de Wardener
Journal: Br Med J Date: 1970-10-17

6. Renal function in analgesic nephropathy.

Authors: T W Steele; A Z Györy; K D Edwards
Journal: Br Med J Date: 1969-04-26

7. Papillary necrosis in experimental analgesic nephropathy.

Authors: B M Saker; P Kincaid-Smith
Journal: Br Med J Date: 1969-01-18

8. Papillary necrosis in rats caused by aspirin and aspirin-containing mixtures.

Authors: R S Nanra; P Kincaid-Smith
Journal: Br Med J Date: 1970-09-05

9. Analgesic nephropathy. A common form of renal disease in Australia.

Authors: P Kincaid-Smith
Journal: Med J Aust Date: 1969-12-06 Impact factor: 7.738

9 in total

11 in total

1. [Not Available].

Authors: K Menges
Journal: Schmerz Date: 1987-09 Impact factor: 1.107

2. TRPM2 channels mediate acetaminophen-induced liver damage.

Authors: Ehsan Kheradpezhouh; Linlin Ma; Arthur Morphett; Greg J Barritt; Grigori Y Rychkov
Journal: Proc Natl Acad Sci U S A Date: 2014-02-03 Impact factor: 11.205

Review 3. Paracetamol.

Authors: T J Meredith; R Goulding
Journal: Postgrad Med J Date: 1980-07 Impact factor: 2.401

Paracetamol and renal damage.

1. Renal concentrating defect in Sjogren's syndrome.

2. Renal tubular acidosis, glomerulonephritis and immunologic factors in Sjögren's syndrome.

3. Phenacetin nephropathy.

4. Paracetamol and the kidney.

5. Phenacetin nephropathy, with particular reference to the effect of surgery.

6. Renal function in analgesic nephropathy.

7. Papillary necrosis in experimental analgesic nephropathy.

8. Papillary necrosis in rats caused by aspirin and aspirin-containing mixtures.

9. Analgesic nephropathy. A common form of renal disease in Australia.

1. [Not Available].

2. TRPM2 channels mediate acetaminophen-induced liver damage.

Review 3. Paracetamol.

Review 4. Analgesic nephropathy: a reassessment of the role of phenacetin and other analgesics.

5. Analgesic nephropathy in the United Kingdom: Incidence, clinical features and pathogenesis.

6. The metabolism and toxicity of paracetamol in Sprague-Dawley and Wistar rats.

Review 7. Aspirin, paracetamol and non-steroidal anti-inflammatory drugs. A comparative review of side effects.

8. [Toxic nephropathies (author's transl)].

9. Evidence for the nephrotoxicity of analgesics.

10. Frequency of renal impairment in paracetamol overdose compared with other causes of acute liver damage.